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SPECIALTIES

When “Type 2” Isn’t Type 2: Clues to Type 3c Diabetes

Pancreas model, glucose meter, and clinical assessment representing type 3c diabetes diagnosis and pancreatogenic diabetes.

A patient develops diabetes in adulthood, so Type 2 diabetes may seem like the obvious diagnosis. However, what if that patient also has chronic pancreatitis, unexplained weight loss, pancreatic surgery, or symptoms of poor nutrient absorption? Those details can change the clinical picture. Careful evaluation can reveal Type 3c diabetes …

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One Drug Isn’t Enough: When Should Clinicians Combine Treatments for Painful Diabetic Neuropathy?

Clinician discussing diabetic neuropathy pain treatment and combination therapy options with a patient using an anatomical foot model.

Finding the right diabetic neuropathy pain treatment can be challenging when a well-chosen first medication provides only partial relief. Burning, shooting pain, tingling, and allodynia can continue to disrupt sleep, mobility, mood, and daily function. Fortunately, clinicians do not always have to choose between abandoning a partially effective drug and …

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Diagnosed Younger: Does Type 1 Onset Shape Later Risk?

Child, teenager, and adult with type 1 diabetes illustrating how age at onset may relate to long-term complication risks.

Does being diagnosed with type 1 diabetes at age 6 carry the same long-term risks as being diagnosed at 16? Researchers have been asking that question for years. Increasingly, evidence suggests that age at type 1 diabetes onset may help explain differences in complication patterns later in life. However, age …

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After Gestational Diabetes, Could Your Neighborhood Shape Your Future Type 2 Risk?

Mother walking with her baby in a walkable neighborhood, illustrating gestational diabetes prevention and future Type 2 diabetes risk.

Diabetes prevention remains important long after a pregnancy affected by gestational diabetes. For people who have had gestational diabetes, the years after delivery are an important window for lowering the risk of Type 2 diabetes. Yet healthy choices do not happen in a vacuum. Where someone lives may affect whether …

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Beyond hs-CRP: Could suPAR Reveal Hidden Heart Risk in Type 2 Diabetes?

suPAR biomarker blood test with heart model and glucose meter representing cardiovascular risk in type 2 diabetes

People with type 2 diabetes can face substantial cardiovascular risk even when clinicians address familiar risk factors such as LDL cholesterol, blood pressure, smoking, and blood glucose. Could another blood marker help reveal some of the risk that remains? Emerging research on the suPAR biomarker in diabetes suggests it may …

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Two Shots a Year for Hypertension? How RNA Silencing Could Transform Cardiometabolic Care

RNAi hypertension diabetes therapy concept showing an investigational injection, blood pressure monitor, liver, heart, and kidneys.

Poor medication persistence remains one of the hardest barriers to long-term blood pressure control. For people with diabetes, the stakes are especially high because hypertension adds to cardiovascular and kidney risk. Now, research into RNAi for hypertension in people with diabetes is raising an intriguing possibility: could an injection given …

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GLP-1s and Vision Loss: What Prescribers Should Know About the Emerging NAION Signal

Patient eye with semaglutide injection illustrating the potential GLP-1 NAION risk and sudden vision loss.

GLP-1 receptor agonists have transformed type 2 diabetes and obesity treatment, but a rare vision safety signal deserves clinicians’ attention. Emerging evidence has raised concerns about a potential NAION risk with GLP-1 therapy, particularly with semaglutide (Ozempic, Rybelsus, and Wegovy). Non-arteritic anterior ischemic optic neuropathy (NAION) can cause sudden, usually …

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Why Are We Ignoring the Gold Standard for Healing Diabetic Foot Ulcers?

Clinician applying a knee-high offloading device to help treat a diabetic foot ulcer and reduce plantar pressure.

Diabetic foot ulcer offloading is one of the most important parts of treating a neuropathic plantar ulcer, yet the most effective approaches are still not routinely used. Non-removable knee-high devices, including total contact casts and non-removable walkers, can reduce damaging pressure while supporting wound healing. So why does a treatment …

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When Diabetes Technology Damages the Skin: Keeping Patients on CGMs and Insulin Pumps

CGM skin irritation around a continuous glucose monitor and insulin pump adhesive sites

Continuous glucose monitors (CGMs) and insulin pumps can transform diabetes management, but the technology only works when patients can comfortably keep wearing it. CGM skin irritation can turn a valuable device into a daily source of itching, redness, pain, or damaged skin. In some cases, the reaction becomes severe enough …

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Your Eye Exam May Be Predicting More Than Vision Loss: AI Is Finding Hidden Diabetes Risks

Retinal AI analysis identifying cardiovascular, kidney, and metabolic risks in a patient with diabetes

For people with diabetes, a retinal photograph has traditionally answered one major question: Is diabetic retinopathy developing? However, artificial intelligence is beginning to uncover much more. Emerging retinal AI models for systemic risk assessment can detect patterns associated with cardiovascular disease, kidney disease, blood pressure, and metabolic health. As a …

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