Prevention

New research shows the prediabetes exercise response may differ by glucose phenotype, highlighting the potential for more personalized prevention plans.

TrialNet’s ASCEND T1D trial compares ATG with teplizumab to explore new ways to delay progression of Stage 2 type 1 diabetes.

Low potassium is usually viewed through a cardiovascular lens, especially in patients with heart failure. However, emerging evidence suggests clinicians may have another reason to pay attention. New research examining the relationship between hypokalemia and diabetes risk found that lower serum potassium levels were associated with a greater risk of …

Diabetes prevention remains important long after a pregnancy affected by gestational diabetes. For people who have had gestational diabetes, the years after delivery are an important window for lowering the risk of Type 2 diabetes. Yet healthy choices do not happen in a vacuum. Where someone lives may affect whether …

Continuous glucose monitoring has changed how clinicians and people with diabetes think about glucose control. Yet the next question is more important than whether CGM improves A1C or Time in Range. Can it prevent events that send patients to the emergency department or hospital? Growing evidence suggests that CGM may …

Efforts to prevent or delay type 1 diabetes have traditionally focused on the autoimmune attack that destroys insulin-producing beta cells. However, emerging research suggests metabolic stress may also influence how quickly vulnerable people progress to clinical disease. A 2026 TrialNet analysis found that autoantibody-positive people with overweight or obesity who …

Could preventing a common viral infection also prevent some cases of type 1 diabetes? Researchers have pursued that question for decades, and the first human vaccine studies are providing important clues. The idea of using a Coxsackievirus vaccine to help prevent type 1 diabetes focuses on certain Coxsackie B viruses, …

Continuous glucose monitors (CGMs) and insulin pumps can transform diabetes management, but the technology only works when patients can comfortably keep wearing it. CGM skin irritation can turn a valuable device into a daily source of itching, redness, pain, or damaged skin. In some cases, the reaction becomes severe enough …

For many people with diabetes, lowering LDL cholesterol is a major part of preventing heart attack and stroke. Yet an important clinical puzzle remains. Why do some patients experience cardiovascular events even after LDL reaches recommended targets? Growing evidence points toward lipoprotein(a), or Lp(a), as one possible piece of that …

Diabetes research is moving beyond blood sugar measurements and insulin therapy into an exciting new frontier. One of the most promising areas involves microRNAs, tiny RNA molecules that quietly regulate hundreds of genes throughout the body. Although they are microscopic, their influence on insulin production, inflammation, and blood vessel health …