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The Treatment Stopped—Did the Benefit Last? New Baricitinib Data in Type 1 Diabetes

Baricitinib type 1 diabetes research concept showing beta-cell preservation and follow-up after treatment ends.

New follow-up research on baricitinib for type 1 diabetes addresses a crucial question: what happens after the drug is stopped? The original BANDIT trial showed that 48 weeks of oral baricitinib helped preserve beta-cell function in people with recently diagnosed type 1 diabetes. However, new follow-up research examines participants through …

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Beyond hs-CRP: Could suPAR Reveal Hidden Heart Risk in Type 2 Diabetes?

suPAR biomarker blood test with heart model and glucose meter representing cardiovascular risk in type 2 diabetes

People with type 2 diabetes can face substantial cardiovascular risk even when clinicians address familiar risk factors such as LDL cholesterol, blood pressure, smoking, and blood glucose. Could another blood marker help reveal some of the risk that remains? Emerging research on the suPAR biomarker in diabetes suggests it may …

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Can Weight Loss Delay Type 1 Diabetes? What the Pre-Symptomatic Data Really Show

Healthy food, exercise shoes, glucose meter, scale, and pancreas illustration representing weight and type 1 diabetes prevention research.

Efforts to prevent or delay type 1 diabetes have traditionally focused on the autoimmune attack that destroys insulin-producing beta cells. However, emerging research suggests metabolic stress may also influence how quickly vulnerable people progress to clinical disease. A 2026 TrialNet analysis found that autoantibody-positive people with overweight or obesity who …

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A Type 1 Breakthrough: Can We Transplant Islets With Less Toxic Immunosuppression?

Medical illustration of transplanted pancreatic islet cells protected from immune attack during experimental type 1 diabetes treatment.

Donor islet transplantation has long offered an intriguing possibility for people with severe type 1 diabetes: restore the body’s ability to make insulin instead of only replacing insulin from the outside. However, there has always been a major tradeoff. Patients need powerful immunosuppressive drugs to keep transplanted cells alive, and …

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Two Shots a Year for Hypertension? How RNA Silencing Could Transform Cardiometabolic Care

RNAi hypertension diabetes therapy concept showing an investigational injection, blood pressure monitor, liver, heart, and kidneys.

Poor medication persistence remains one of the hardest barriers to long-term blood pressure control. For people with diabetes, the stakes are especially high because hypertension adds to cardiovascular and kidney risk. Now, research into RNAi for hypertension in people with diabetes is raising an intriguing possibility: could an injection given …

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Could Dissolving Microneedle Patches Make Diabetes Injections a Thing of the Past?

Dissolving microneedle patch for diabetes shown on the skin alongside insulin delivery and glucose monitoring technology.

For millions of people who use injectable diabetes medications, treatment can mean living with needles every day. What if a small skin patch could eventually deliver insulin or other therapies with far less discomfort? Researchers studying microneedle patches for diabetes hope to make that possibility practical. These experimental patches use …

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GLP-1s and Vision Loss: What Prescribers Should Know About the Emerging NAION Signal

Patient eye with semaglutide injection illustrating the potential GLP-1 NAION risk and sudden vision loss.

GLP-1 receptor agonists have transformed type 2 diabetes and obesity treatment, but a rare vision safety signal deserves clinicians’ attention. Emerging evidence has raised concerns about a potential NAION risk with GLP-1 therapy, particularly with semaglutide (Ozempic, Rybelsus, and Wegovy). Non-arteritic anterior ischemic optic neuropathy (NAION) can cause sudden, usually …

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Why Are We Ignoring the Gold Standard for Healing Diabetic Foot Ulcers?

Clinician applying a knee-high offloading device to help treat a diabetic foot ulcer and reduce plantar pressure.

Diabetic foot ulcer offloading is one of the most important parts of treating a neuropathic plantar ulcer, yet the most effective approaches are still not routinely used. Non-removable knee-high devices, including total contact casts and non-removable walkers, can reduce damaging pressure while supporting wound healing. So why does a treatment …

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The Hidden Hyperglycemia Trigger: When Dehydration Makes Blood Sugar Worse

Person with diabetes reaching for water beside a glucose meter, illustrating how dehydration can worsen high blood sugar.

For people with diabetes, an unexpected glucose spike may have a less obvious cause than food or missed medication. Dehydration and high blood sugar can create a self-reinforcing cycle. When the body loses too much fluid, glucose becomes more concentrated in the bloodstream. At the same time, rising glucose can …

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