New follow-up research on baricitinib for type 1 diabetes addresses a crucial question: what happens after the drug is stopped? The original BANDIT trial showed that 48 weeks of oral baricitinib helped preserve beta-cell function in people with recently diagnosed type 1 diabetes. However, new follow-up research examines participants through …
Read More »Beyond hs-CRP: Could suPAR Reveal Hidden Heart Risk in Type 2 Diabetes?
People with type 2 diabetes can face substantial cardiovascular risk even when clinicians address familiar risk factors such as LDL cholesterol, blood pressure, smoking, and blood glucose. Could another blood marker help reveal some of the risk that remains? Emerging research on the suPAR biomarker in diabetes suggests it may …
Read More »Can Weight Loss Delay Type 1 Diabetes? What the Pre-Symptomatic Data Really Show
Efforts to prevent or delay type 1 diabetes have traditionally focused on the autoimmune attack that destroys insulin-producing beta cells. However, emerging research suggests metabolic stress may also influence how quickly vulnerable people progress to clinical disease. A 2026 TrialNet analysis found that autoantibody-positive people with overweight or obesity who …
Read More »Could a Virus Vaccine Help Prevent Type 1 Diabetes? Inside the Human Trials
Could preventing a common viral infection also prevent some cases of type 1 diabetes? Researchers have pursued that question for decades, and the first human vaccine studies are providing important clues. The idea of using a Coxsackievirus vaccine to help prevent type 1 diabetes focuses on certain Coxsackie B viruses, …
Read More »A Type 1 Breakthrough: Can We Transplant Islets With Less Toxic Immunosuppression?
Donor islet transplantation has long offered an intriguing possibility for people with severe type 1 diabetes: restore the body’s ability to make insulin instead of only replacing insulin from the outside. However, there has always been a major tradeoff. Patients need powerful immunosuppressive drugs to keep transplanted cells alive, and …
Read More »Two Shots a Year for Hypertension? How RNA Silencing Could Transform Cardiometabolic Care
Poor medication persistence remains one of the hardest barriers to long-term blood pressure control. For people with diabetes, the stakes are especially high because hypertension adds to cardiovascular and kidney risk. Now, research into RNAi for hypertension in people with diabetes is raising an intriguing possibility: could an injection given …
Read More »Could Dissolving Microneedle Patches Make Diabetes Injections a Thing of the Past?
For millions of people who use injectable diabetes medications, treatment can mean living with needles every day. What if a small skin patch could eventually deliver insulin or other therapies with far less discomfort? Researchers studying microneedle patches for diabetes hope to make that possibility practical. These experimental patches use …
Read More »GLP-1s and Vision Loss: What Prescribers Should Know About the Emerging NAION Signal
GLP-1 receptor agonists have transformed type 2 diabetes and obesity treatment, but a rare vision safety signal deserves clinicians’ attention. Emerging evidence has raised concerns about a potential NAION risk with GLP-1 therapy, particularly with semaglutide (Ozempic, Rybelsus, and Wegovy). Non-arteritic anterior ischemic optic neuropathy (NAION) can cause sudden, usually …
Read More »Why Are We Ignoring the Gold Standard for Healing Diabetic Foot Ulcers?
Diabetic foot ulcer offloading is one of the most important parts of treating a neuropathic plantar ulcer, yet the most effective approaches are still not routinely used. Non-removable knee-high devices, including total contact casts and non-removable walkers, can reduce damaging pressure while supporting wound healing. So why does a treatment …
Read More »The Hidden Hyperglycemia Trigger: When Dehydration Makes Blood Sugar Worse
For people with diabetes, an unexpected glucose spike may have a less obvious cause than food or missed medication. Dehydration and high blood sugar can create a self-reinforcing cycle. When the body loses too much fluid, glucose becomes more concentrated in the bloodstream. At the same time, rising glucose can …
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