Most with long-term diagnosis foud to continue to secrete low levels of insulin… In a large-population based study, researchers used sensitive C-peptide assays to demonstrate that 43-74% people with longstanding (>5 years) type 1 diabetes are microsecretors of endogenous insulin with C-peptide levels. The Scottish researchers measured the occurrence of …
Read More »Type 2 Diabetes Control with GLP-1 Agonist and Basal Insulin Combination
Glucose regulation and weight management are very important factors when treating type 2 diabetes patients… Prior studies have shown that glucagon-like peptide receptor agonist are beneficial not only for better glucose control but also helpful in weight reduction in patients with type 2 diabetes. Other studies and recommendations on type …
Read More »Change Language to Combat Feelings of Failure
A patient presented for outpatient diabetes education stating, “I really don’t know why I am here. I know I need to lose weight. I don’t know what else you can tell me.” She was reassured when I told her that there are people who are a perfect weight, exercise regularly, …
Read More »Measuring CKD and Cognitive Impairment in Type 2 African Americans
Participants with CKD had significantly poorer processing speed and working memory…. Both type 2 diabetes and chronic kidney disease (CKD) have been associated with structural brain changes. In previous studies, people with type 2 diabetes have been shown to have reduced total gray matter and WM volume, as well as …
Read More »Maternal Glycemia Linked to Childhood Obesity
Maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and metabolic dysfunction…. A secondary analysis of a mild gestational diabetes mellitus treatment trial long-term follow-up study looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and …
Read More »Researchers Uncover More Clues to How Drug Reverses Obesity, Diabetes, Fatty Liver Disease
Amlexanox increases the level of a second messenger molecule called cAMP which then increases the rate by which cells burn fat… Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar …
Read More »Eye Scan Predicts Peripheral Neuropathy in Type 1 Diabetes
Corneal confocal microscopy (CCM) can predict incipient peripheral neuropathy in patients with type 1 diabetes… The technique involves the examination of unmyelinated nerve fibers at high magnification using a laser-scanning corneal confocal microscope to image the subbasal nerve plexus of the patient’s cornea. Increased severity of diabetic peripheral neuropathy is …
Read More »Type 2 Diabetes Remission Very Rare in Non-Bariatric Surgery Patients
American researchers looked at data on over 120,000 type 2 patients to find out what rates of remission were…. Previous studies have shown that bariatric surgery can result in long-term weight loss, improvement in cardiovascular risk factors, and a reduction in mortality rate of 15% from baseline. However, in a …
Read More »Obesity and CHD Association in Type 2 Diabetes Patients
Are obesity and CHD truly associated?… Researchers from the U.S. and China examined data on 30,434 diabetic patients from the Louisiana State University Hospital-Based Longitudinal Study (10,955 men and 19,479 women). Patients included were 30-95 years of age without a history of CHD or stroke in the Louisiana State University …
Read More »Genetic Variations Associated with Traits Underlying Type 2 Diabetes in Mexican-Americans
But narrowing down the exact genes responsible proves to be complicated… While people of Mexican ancestry are nearly twice as likely to develop type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin. In an effort to understand …
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