Mutations in the ankyrin-B gene cause fat cells to soak up more glucose, setting the stage for obesity and insulin resistance… Ankyrin-B was discovered more than 30 years ago by researcher Vann Bennett at Duke University School of Medicine and the Howard Hughes Medical Institute. The gene plays a role …
Read More »Bromocriptine for High Dose Insulin Therapy Type 2 Patients
Treatment can decrease amount of total daily insulin dose due to insulin sensitizer properties… As the duration of diabetes diagnosis lengthens for patients, management of the disease gets more difficult. Insulin therapy is very effective in treating hyperglycemic events, however it carries unwanted side effects such as hypoglycemia and weight …
Read More »Impact of Exercise in Type 2 Diabetes Patients
Rise in cerebral blood flow studied as cause of fatigue during physical activity… The development of fatigue is still a complication among type 2 diabetics. During exercise, a person with diabetes will experience a loss of muscle generating capacity. Currently, the mechanism of action of reduced exercise tolerance is still …
Read More »The Outcome of DPP-4 Inhibitors in Type 2 Patients on Hemodialysis
Decreased chance of hypoglycemic event and greater safety profile shown in use of this therapy… Diabetes is the main reason for renal failure in today’s population. Currently, the main treatment option for a hemodialysis diabetic patient is insulin therapy. Insulin therapy is a difficult regimen for many patients due to …
Read More »Ancestral Diets Can Determine Vulnerability to Type 2 Diabetes
In a 12-year study with over 50 generations, rats who had undernourished ancestors were found to be more susceptible to diabetes and other metabolic diseases… The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today’s changing environment. New …
Read More »Type 2 Diabetes Has Adverse Effects on Memory and Learning Abilities in Older Adults
Scores of the diabetes patients decreased by an additional 12 percent during the two-year period… Type 2 diabetes is known to put individuals at risk for numerous health complications. Now a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) sheds new light on the often overlooked toll …
Read More »Fat Fish Illuminate Human Obesity
Binge-eating cavefish share mutated gene with some obese people. Blind cavefish have evolved to be starvation resistant, constantly hungry, and fat but healthy. New research shows they share genetic mutations with some obese people. Narration by study co-author Nicolas Rohner. Blind cavefish that have adapted to annual cycles of starvation …
Read More »DPP-4 Inhibitors and Type 2 Elderly Patients
In a study, older patients taking Januvia reduced their A1c’s without an increased risk of hypoglycemia…. The mortality rate for elderly individuals with type 2 diabetes is twice that of elderly individuals without type 2 diabetes. That is why it is very important for elderly individuals with diabetes to optimize …
Read More »Long-term Glucose Variability and Cognitive Function in Older Type 2 Diabetic Patients
Visit-to-visit glucose variability may play a key role in cognitive function in type 2 diabetic patients…. Previous studies have shown an association with hypoglycemic/hyperglycemic episodes and change in cognitive function in diabetic patients, however it remains uncertain whether long-term exposure to glucose variability prompts cognitive changes in diabetic patients. A …
Read More »Spousal Support Critical for Type 2 Diabetic Patients with Mental Illness
Researchers analyzing social networks found that type 2 diabetic patients with mental illness had smaller social networks… Social support has been linked with successful adoption of lifestyle modifications for people with type 2 diabetes. Patients who suffer from type 2 diabetes and a mental disorder often have diminished social networks …
Read More »
Diabetes In Control. A free weekly diabetes newsletter for Medical Professionals. News and information for Medical Professionals.