The new drug apparently works by stabilizing metabolites of an omega-3 fatty acid called DHA… Researchers Bruce Hammock at the University of California, Davis, and Joan Claria at the University of Barcelona found that an enzyme called soluble epoxide hydrolase, or sEH, inhibitor both prevented the onset of diabetes and …
Read More »Type 2 Diabetes Linked with Colorectal Cancer
A longer duration of obesity also increased risk of colorectal cancer for diabetic patients… Dutch researchers have assessed the risk of colorectal cancer associated with type 2 diabetes, as compared with a nondiabetic reference population. They conducted an observational population-based cohort study within the Clinical Practice Research Datalink (1987–2012). All …
Read More »FDA Approves Maestro Rechargeable System (EnteroMedics) for Treatment of Obesity.
The Maestro Rechargeable System is indicated for treatment of patients aged at least 18 years with a BMI of 35 to 45 with at least one obesity-related condition and who have failed to lose weight on a weight loss program. The novel device is the first to target the nerve …
Read More »Dr. David Platt – BTI320, a New Approach to Therapy
Steve Freed: Please tell us a little about yourself and this new compound, BTI320. Dr. David Platt: My area of expertise is the recognition between carbohydrate and protein. In my previous two companies, I developed drugs for a recognition between sugar and protein. In one case, it was a protein that …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #27: Diabetes in Childhood and Adolescence
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP The vast majority of cases of diabetes in children are type 1, caused by autoimmune destruction of beta cells in the pancreatic islets. A steady increase in the incidence of type 1 diabetes has been reported worldwide (average increase 2.5-3% per year …
Read More »CGM Best Fit for Active Type 1 Patients
Janelle, an RN, is 36 years old with type 1 diabetes. She has a busy life between family and work. She eats healthy, exercises regularly, and wears a pump but occasionally has severe hypoglycemia, especially during exercise and at night. When I met her, I recommended she wear a continuous …
Read More »Change Talk: Childhood Obesity
Change Talk: Childhood Obesity is a role-play simulation where you take the role of a healthcare provider and engage in a practice conversation with a virtual mother and her child. Through the conversation, you learn to apply Motivational Interviewing (MI) techniques to help them identify motivation for change, supporting them …
Read More »New Insulin Glargine 300 Effective in Type 1 Diabetes
Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …
Read More »Sulfonylureas, Insulin, and Metformin Cancer Risks for Patients with Type 2 Diabetes
Can metformin reduce the risk of cancer for those with type 2 diabetes?… In previous studies, metformin has been shown to decrease the risk of cancer in type 2 diabetes. A recent meta-analysis showed a 34% reduction in the incidence of any cancer and a 33% reduction in cancer mortality; …
Read More »Reduction of Renal Function and Exercise Capacity in Type 1 Diabetic Adolescents
Insulin resistance with increasing LDL cholesterol were related to low peak volume of oxygen level… Diabetic nephropathy and cardiovascular disease are strongly related in adults with type 1 diabetes, yet little is known about this relationship in adolescents prior to the onset of detectable clinical disease. The researchers hypothesized that …
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