Conditions

Offspring count higher for unaffected siblings, adult-onset type 1 patients…. The Finnish researchers assessed fertility, defined as number of offspring, in the affected and unaffected siblings included in the T1DGC. Clinical information was collected from participants aged ≥18 years at the time of examination. The number of offspring of affected …

Degree of glycemic control is investigated for excess risk of death due to cardiovascular cause…. When compared to the general population, patients with type 1 diabetes are at increased risk of premature death. The most common cause of death is cardiovascular disease in patients over thirty years of age. Adequate …

A previous history of severe hypoglycemia is linked to increased death rates after a cardiovascular event in type 1 diabetes patients… Hypoglycemia is the most common and life-threatening complication of type 1 diabetes. The average type diabetes patient experiences about two episodes of hypoglycemia per week. Patients with type 1 …

Macrophages, a type of immune cell, were found invading pancreatic tissue during the early stages of the disease… Type 2 diabetes is characterized by the loss of beta cells, reduced insulin production and low-grade systemic inflammation. A new study compared healthy mice to obese mice that developed diabetes. The mice were followed …

Free fatty acids may play an important role in the development of diabetes and cardiovascular diseases… Diabetes increases the risk of cardiovascular disease and stroke. About 50% of people with diabetes die of cardiovascular disease. Hyperglycemia causes an increase in free fatty acids (FFA), which is derived from lipolysis. An …

Catheter-based procedure expected to decrease hormone responsible for appetite… Bariatric embolization is a minimally invasive technique whereby a small catheter is introduced into the groin or wrist and guided into the left gastric artery that supplies the upper stomach. Particles smaller than a grain of sand are then injected into …

Add-on of saxagliptin plus dapagliflozin shows greater improvements in glycemic control versus the use of single drug with metformin…. Because of the progressive nature of the disease, patients with type 2 diabetes regularly require various antidiabetic agents to achieve and maintain glycemic control. This study assessed the efficacy and safety …

Delayed diagnosis leading to high instances of DKA in children… Type 1 is the most common form of diabetes in diagnosed children and adolescents. In 2009, the CDC reported the prevalence at 1.93 in every 1,000 children and adolescents, whereas type 2 diabetes affects 0.24 in every 1,000. In a …

Stress hormones prompt increase of glucose uptake…. Researchers found that brown adipose tissue (brown fat), which is active in adults, acts as one of the bodily tissues that can be encouraged to take up glucose from the bloodstream to use as a fuel source to create body heat. Increasing the …

Twice-daily regimen found to increase LDL, genital infections compared to benefits of once-daily regimen… An investigational SGLT2 inhibitor remogliflozin etabonate showed significant benefits for glucose control in type 2 diabetics in a randomized study. The study enrolled 241 participants with a mean age of 53, and who had a mean …