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CONDITIONS

Phentermine and Topirimate ER (Qsymia) Studied for Type 2 Diabetes Patients

Diabetic patients can lose weight with medication specific for weight loss... In two randomized, double-blind and placebo-controlled studies, the safety and efficacy of treatment with phentermine (PHEN) and topiramate ER (TPM ER) (Qsymia) plus lifestyle for weight loss and glycemic benefits were measured. The studies included obese/overweight adults with type 2 diabetes. …

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Beloranib Demonstrates Weight Loss in Hypothalamic Injury-Associated Obesity

The drug, a first-in-class MetAP2 inhibitor, was well-tolerated and also improved cardiovascular disease risk factors… Zafgen has announced that ZAF-221, a randomized, double-blind, placebo-controlled Phase 2 clinical trial of beloranib, a MetAP2 inhibitor, in 14 adults with hypothalamic injury associated obesity, or HIAO, met the primary efficacy endpoint of weight …

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Two MicroRNAs Identify Prediabetes

Serum levels of 2 microRNAs, miR-192 and miR-193b, can be used to identify individuals with prediabetes, researchers report… The uncontrolled hyperglycemic excursions associated with prediabetes are stressful for the body, and miRNAs are thought to be critical regulators of stress. Dr. Marcelina Párrizas from Diabetes and Obesity Research Laboratory, Barcelona, …

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Low Birth Weight Increases Type 2 Diabetes Risk

A number of related factors could alert physicians to a greater likelihood that a patient who had low birth weight is at greater risk… A new study of more than 3,000 women confirms that low birthweight predicts an increased risk of type 2 diabetes in adulthood and reports which intermediating …

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Obesity Not Unhealthy for Some

Obesity does not always go hand in hand with metabolic changes in the body that can lead to diabetes, heart disease and stroke, according to a new published study… In a study at Washington University School of Medicine, researchers found that a subset of obese people do not have common …

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