Resources

The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …

Optimum HbA1c level yet to be determined… HbA1c is strongly related to the development of diabetes complications, but it is still controversial as to which HbA1c level to strive for in the treatment of type 1 diabetes. Swedish researchers evaluated HbA1c, followed from diagnosis, as a predictor of severe microvascular …

In the DPP and DPP-OS trials, diabetes was prevented or delayed with metformin or ILS when directed at weight loss and increased physical activity… Previous randomized clinical trials such as the Diabetes Prevention Program and the long-term follow-up trial, the Diabetes Prevention Program Outcomes study, evaluated metformin and an intensive …

However, advancement in medications and better controlled regimens may be contributing to a decline in psychiatric disorders among this population… We know from previous studies and research that there is a increased risk and prevalence for depression in the diabetic population. Other trials have also linked diabetes with different subtypes …

Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …

Depressive symptoms have been associated with type 2 diabetes mellitus (T2DM), but less is known about other anxiety disorders that can be comorbid or exist without depression… This study examined patients at risk for type 2 diabetes and its correlation to anxiety, depression or metabolic syndrome in the at risk …

Inadequate access to primary care means that deaf people have a higher risk of developing type 2 diabetes, high blood pressure, and heart disease… The research, conducted at the School for Social and Community Medicine at the University of Bristol, compared the health of deaf people to that of people …

Popular weight loss strategy improves satiety and decreases fat mass, but increases risk of metabolic disease… Some of the potential mechanisms that account for weight loss associated with high-protein diets involve increased secretion of satiety hormones (GIP, GLP-1), reduced orexigenic hormone secretion (ghrelin), the increased thermic effect of food and …

Crisis episodes signified uncontrolled diabetes and increased risk of complications… Researchers evaluated data for 13,551 older patients with new-onset diabetes between 2000 and 2002, including 34,517 with hyperglycemic crisis episodes and 9,034 without (controls). Follow-up was conducted until 2011. Participants were classified into three subgroups: young elderly (65-74 years), moderately …

  From Dave Joffe, Editor-in-chief, Diabetes In Control: Most of us are used to standing on our feet for long hours each day, whether it’s behind a pharmacy counter, going from exam room to exam room, or lecturing in a classroom. At the end of the day nothing feels as …