Dr. Aaron Vinik addresses the question of why so much current diabetes therapy is focused on lowering blood glucose levels despite evidence that for some cardiovascular issues, this doesn’t have as much of an impact as other drugs which may have less BG-lowering capacities….
Read More »Knowledge of Onset, Peak, and Duration of Action of Meds Prevents a Trip to the ER
It was 8:15 pm. A patient who lives alone called me. “Joy, I just mixed up my Humalog and my Lantus. I took 20 units of Humalog but I was supposed to take 20 units of Lantus, and I took 10 units of Lantus.” I knew that the onset of …
Read More »Diabetes Mellitus 101 for Cardiologists, Part 7
In this week’s Homerun Slides, Dr. Stanley Schwartz discusses the “Adipocytokine Syndrome” which he describes as “A New Model for Insulin Resistance and Beta Cell Dysfunction.” He also reviews and compares several diabetes drugs’ effects on insulin resistance and beta cell function as well as other diabetes comorbidities…. To download these …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #19: Macrovascular Disease in Diabetes
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Atherosclerosis For any given age, level of cholesterol or BP, the risk of atherosclerotic cardiovascular disease (CVD) is 3 to 5-fold higher among patients with diabetes compared with subjects without diabetes. Macrovascular complications include fatal and non-fatal coronary heart disease (CHD) events, …
Read More »Severe Hypoglycemia Associated with CV Mortality Risk in Type 1
A previous history of severe hypoglycemia is linked to increased death rates after a cardiovascular event in type 1 diabetes patients… Hypoglycemia is the most common and life-threatening complication of type 1 diabetes. The average type diabetes patient experiences about two episodes of hypoglycemia per week. Patients with type 1 …
Read More »Is Type 2 Diabetes an Inflammatory Disease?
Macrophages, a type of immune cell, were found invading pancreatic tissue during the early stages of the disease… Type 2 diabetes is characterized by the loss of beta cells, reduced insulin production and low-grade systemic inflammation. A new study compared healthy mice to obese mice that developed diabetes. The mice were followed …
Read More »Link between Free Fatty Acids and Acute MI, Type 2 Diabetes
Free fatty acids may play an important role in the development of diabetes and cardiovascular diseases… Diabetes increases the risk of cardiovascular disease and stroke. About 50% of people with diabetes die of cardiovascular disease. Hyperglycemia causes an increase in free fatty acids (FFA), which is derived from lipolysis. An …
Read More »Doctors Perform the First Bariatric Embolization to Treat Obesity
Catheter-based procedure expected to decrease hormone responsible for appetite… Bariatric embolization is a minimally invasive technique whereby a small catheter is introduced into the groin or wrist and guided into the left gastric artery that supplies the upper stomach. Particles smaller than a grain of sand are then injected into …
Read More »Hemodialysis at Home Provides Better Outcomes
Convenience, cost, frequency contribute to decrease in mortality rates… A report from American Society of Nephrology (ASN) Kidney Week 2014 showed that home dialysis therapies may help prolong the lives of patients with kidney failure when compared to hemodialysis treatments administered in medical centers. It was shown that home dialysis …
Read More »Any Pain Medication Said Effective When Treating Diabetic Nerve Pain
Prescribers can consider cheaper drugs until further studies are done…
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