Resources

David Levy, MD, FRCP Drugs acting on the incretin system (entero-insular axis) (Fig. 6.2) The incretin effect Bayliss and Starling inferred the existence of gut-derived substances affecting carbohydrate metabolism more than a century ago, but the incretin effect was not described until 1969: the observation that for a given achieved level …

Peter Katzmarzyk, PhD, discusses the growing problem of childhood obesity which frequently contributes to the earlier development of adult type 2 diabetes. He also mentions that, particularly in the southern U.S., there are more and more incidences of type 2 in children and teens being reported. More videos with Dr. …

Peter Katzmarzyk, PhD, talks about how, even though dieting and exercise should be part of every patient’s regimen, this can be extremely difficult in certain places. He says there are many ways we could improve the physical environment, however, in our towns and cities, including simple things like adding sidewalks …

With this week’s Homerun Slides, we look at the current realities of modern life which seem to be encouraging the development of insulin resistance and how Modern Man is "locked" into a "Seasonal Insulin Resistance Syndrome Physiology"…. To download the complete set of slides in PowerPoint (.ppt) format, just use this …

From our publisher, Steve Freed, comes this thought-provoking discussion of how better diabetes control can impact cost, quality of life and mortality…

Diabetic peripheral neuropathy can have an effect on balance… Previous studies show that patients with diabetic peripheral neuropathy (DPN) have an altered gait strategy and a fivefold increased risk of falling. Falling is a major health risk, especially with disease progression and in the elderly. Diabetic patients with peripheral neuropathy …

Older individuals are at an increased risk for cardiac autonomic nervous dysfunction…

A multinational team of researchers studied data from over 16,000 patients in the SAVOR-TIMI 53 trial…. Saxagliptin (Onglyza) is a commonly prescribed dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. An international team of researchers examined the effects of saxagliptin on glycemic stability and β-cell function in the …

But the association with between hypertension, diabetes, and dementia is not clear…. Previous studies have found a correlation between individuals with hypertension and diabetes, and the subsequent development of dementia. The purpose of this cross-sectional study was to analyze the effect of diabetes and hypertension on cognitive scores conducted on …

Initial combination therapy of metformin, pioglitazone, and exenatide might be more effective in reducing HbA1c compared to sequential add-on in new-onset diabetic patients… The purpose of this study is to initiate a therapy regimen that will reduce HbA1c, increase insulin secretion, and increase insulin sensitivity. This therapy will also avoid …