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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #48: Biosynthesis, secretion, and action of glucagon Part 2 of 4

Physiologic effects of glucagon: Glucagon acts through binding to specific receptors located at the target cell plasma membrane. The major common effect of glucagon is to activate adenylate cyclase and to increase the intracellular production of cAMP. There is considerable evidence that binding of glucagon to its receptor activates an intermediate transduction process that involves the participation of guanosine triphosphate (GTP), divalent cations, and adenosine (or other similar natural substances).

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Claude Lardinois Full Interview

Dr. Claude Lardinois talks with Diabetes in Control Associate Medical Editor Joy Pape at the 2016 AACE Meeting. Dr. Lardinois discusses amputations and SGLT-2s, and genetic risk factors for cardiovascular issues in diabetes patients. Dr. Claude Lardinois, M.D., FACP, FACE, MACN, has been an endocrinologist in Reno, Nevada for more …

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