Insulin Therapy Center

A novel insulin that automatically adjusts blood sugar may mitigate some of the complications associated with insulin dosing for patients with type 1 diabetes… Self-administered insulin is the most important therapeutic to provide control over blood glucose levels for patients with type 1 diabetes. However, standard insulin therapy introduces a …

David Levy, MD, FRCP Introduction Insulin treatment in type 1 diabetes is substitution/replacement hormone treatment, but replacement is much more variable and difficult to achieve than in other hormone deficiencies (e.g. thyroid, adrenal, gonadal hormones) because of the minute-by-minute variation in insulin secretion by the intact pancreas, which cannot yet be …

Success in finding new stem cells that can produce insulin… Type 1 diabetes is caused by autoimmune disease that leads to the destruction of insulin producing beta cells in the pancreas. The destruction of beta cells in the pancreas can be treated by transplant of pancreatic beta cells or cadaveric …

Glucose regulation and weight management are very important factors when treating type 2 diabetes patients… Prior studies have shown that glucagon-like peptide receptor agonist are beneficial not only for better glucose control but also helpful in weight reduction in patients with type 2 diabetes. Other studies and recommendations on type …

Hypoglycemia was relatively uncommon in the ORIGIN (Outcome Reduction with an Initial Glargine Intervention) trial… ORIGIN trial investigators have published results of their look at treatment with insulin glargine compared with standard care early in the course of dysglycemia, and its effects on hypoglycemia. A total of 12,537 people with …

Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …

Can metformin reduce the risk of cancer for those with type 2 diabetes?… In previous studies, metformin has been shown to decrease the risk of cancer in type 2 diabetes. A recent meta-analysis showed a 34% reduction in the incidence of any cancer and a 33% reduction in cancer mortality; …

The women also experienced reduced beta cell function…. Researchers from the University of Southern California, Los Angeles, assessed associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM …

  The t:flex Pump is designed for patients who require more than 100 units of U-100 insulin per day, such as teenagers with type 1 diabetes and many people with type 2 diabetes. The pump offers the benefits of pump therapy without the frequent reservoir changes required by 200- and …

According to a new study, about 1/3 of people with type 1 diabetes produce insulin, as measured by C-peptide, even upward of 40 years from initial diagnosis… The findings shed new light on the long-accepted belief that patients with type 1 diabetes lose all ability to produce any insulin. The …