Insulin Therapy Center

A “smart” insulin patch mimicking the actions of the pancreas has been tested in mice…. Researchers may have developed a patch that mimics the action of the pancreas; it senses increased levels of blood glucose and consequently releases the amount of insulin necessary to bring blood glucose levels within normal …

Once-daily, single-injection treatment lowered HbA1c levels, decreased body weight and reduced risk for hypoglycemia in type 2 patients…

Peglispro allows slow insulin absorption, but associated with injection site reaction and increased ALT and triglycerides… Peglispro or pegylated lispro insulin is currently under phase III investigation for both type 1 and type 2 diabetes. The large hydrodynamic size of peglispro allows slow insulin absorption and reduces clearance, resulting in …

GLP-1 analog also showed reduction in weight and incidence of hypoglycemia… Dulaglutide (Trulicity) is a glucagon-like peptide analog that is used once weekly to improve blood glucose level. During the open-label, multinational, parallel arm study, researchers compared the safety and efficacy of dulaglutide 0.75mg and 1.5mg to insulin glargine in …

Canagliflozin appears to offer significant benefits when used in conjunction with insulin therapy.

The patient, a woman, 52 years of age, has type 2 diabetes and is on metformin, a GLP-1 agonist, and a long-acting insulin. Over the past few months, I’ve received calls and emails from her every now and then to let me know her glucose levels were rising, but whenever …

  A list from the U.K. of the newest insulins available overseas and in the U.S. What’s New In Insulin Products (PDF) 

A married male patient, 68 years of age, has been prescribed long-acting insulin twice a day because once-daily does not work 24 hours for him, and his dose is large. Therefore breaking it into two smaller injections helps bring down his glucose, but only when he remembers to take his …

  The FDA has approved the t:flex insulin pump for marketing. The pump, manufactured by Tandem Diabetes Care, can store the largest amount of insulin (480 units) of any pump available in the U.S. Designed for people who require more than 80 units of U-100 insulin per day, the t:flex …

In the Pre-POINT pilot study, five of six children who were at extremely high risk of developing type 1 diabetes and who received a high dose of oral insulin had a protective immune response, and the insulin did not cause hypoglycemia… Children at risk for type 1 diabetes, who were …