Insulin Therapy Center

A fall in insulin dose requirement in patients with preexisting diabetes can lead to increased risk of placental dysfunction… Women with preexisting diabetes typically experience an increased need for insulin during the later stages of pregnancy due to an increase in insulin resistance during this time. A drop in insulin …

Drinking grapefruit juice daily can lead to weight loss and help control blood glucose… Grapefruit juice is considered to be high in nutrients while remaining relatively low in calories when compared to other fruit juices. These diets often rely on daily low calorie commitment, which calls into question the true …

Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …

Adding an SGLT2 inhibitor to multiple daily doses of insulin improved glycemic control, benefited weight loss, lowered insulin doses, and no increase in hypoglycemia was seen…   Some patients with inadequately controlled type 2 diabetes still do not achieve glycemic control with multiple daily doses of insulin. Empagliflozin is a …

Typically when we diagnose a type 2 patient we start on the normal pathway of metformin and “diet and exercise” modifications. For many of our patients this regimen makes a significant improvement in their glucose levels and A1c values…. But for those patients who don’t improve, we are then forced …

Dulaglutide shows efficacy in diabetes patients with poor glycemic control already taking multiple oral medications…. Patients with uncontrolled diabetes already taking multiple oral agents often require insulin therapy for better glycemic control but insulin therapy is associated with hypoglycemia and weight gain. Dulaglutide, approved by the FDA in September 2014, …

For people with type 1 diabetes, long-acting insulin may be a better treatment choice than intermediate-acting insulin…. Different types of insulin are used to manage type 1 diabetes with insulin injections. Long-acting insulin takes about one hour to begin lowering blood sugar levels and lasts up to 26 hours, while intermediate-acting …

Insulin-dependent diabetes patients were at an increased risk of post-surgery complications following lumbar fusion including death, sepsis, wound infection and 30-day readmission…. Patients with insulin-dependent diabetes mellitus (IDDM) have an increased risk of a number of postoperative complications after lumbar fusion compared with those who have noninsulin-dependent diabetes mellitus (NIDDM) …

And fatal cardiovascular disease risk is 43% lower for type 1 diabetes patients using insulin pumps over multiple daily injections….  Dr. Gudbjörnsdottir and colleagues in Sweden conducted an observational study using patient data from the Swedish National Diabetes Registry from 1996 till 2014. The data included more than 95% of …

Higher levels of hypothalamic nitric oxide could lead to less insulin clearance and more lipogenesis…. Nitric oxide (NO) is an important neurotransmitter produced in the paraventricular nucleus (PVN) of the hypothalamus. Previous studies suggested that the level of NO was inversely correlated with systemic insulin clearance. However, little is known …