Elevated fasting insulin levels in children aged 3 to 6 years may help predict which children will develop type 2 diabetes as adults… Although researchers did not find the same association for older children and adolescents, they did find an association between body mass index (BMI) in peripubertal years and …
Read More »Vibe Insulin Pump with CGMS Technology
Animas, a division of Johnson & Johnson, has finally won FDA approval for its Vibe insulin pump and continuous glucose monitoring system. The pump is the first to pair with Dexcom’s G4 PLATINUM continuous glucose monitor that samples interstitial fluid every five minutes and provides a trending chart of …
Read More »Increased Mortality with Combining Sulfonylurea and Insulin
About 11,000 patients using both insulin and sulfonylurea were evaluated… Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the differences in outcomes of treatment combinations. Outcome …
Read More »Early Insulin Therapy Makes an Impact
Improved glycemic control can reduce A1c, medical costs and complications… According to a new study, early introduction of insulin could save money, help more patients reach A1c goals and decrease diabetes-related complications and mortality. Currently, insulin therapy for persons with type 2 diabetes is traditionally added to an anti-hyperglycemic regimen …
Read More »Hypoglycemia Increased Risks for CV Events, Death in Diabetic Patients on Insulin
Increased risk seen in both type 1 and type 2 diabetes patients treated with insulin. Insulin-treated patients with diabetes who experience hypoglycemia are also more likely to experience cardiovascular events and die from any cause, according to the current research. The link between hypoglycemia and CV outcomes and death remains …
Read More »Not All Insulin Pens are the Same
Recently, a patient of mine called about her post-meal glucose levels which were increasing.
Read More »Assessing Insulin Administration Technique
An 83-year-old woman who lived alone and was very active in her community was having wide swings in her glucose levels. She reported sometimes waking up hours after dinner with her head in her dinner plate. She did not understand why. She did not have family or caretakers nearby to …
Read More »Remote Wireless Monitoring Can Help Patients Newly Diagnosed with T1
A patient of mine was newly diagnosed with type 1 diabetes. He started on insulin and I taught him about glucose targets; insulin administration, including the signs and symptoms of hypoglycemia; and how to prevent, recognize, and treat hypoglycemia. I also taught him about the “honeymoon period,” which, I told …
Read More »DPP-4 Inhibitors in Combination with Insulin Therapy for Type 2 Diabetes Patients
The addition of a DPP-4 inhibitor decreased HbA1C while not requiring an increase in insulin, and subjects remained weight neutral without experiencing an increase in hypoglycemic events… Currently approved dipeptidyl peptidase-4 (DPP-4) inhibitors include alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin. DPP-4 inhibitors work by enhancing glucose dependent insulin secretion and …
Read More »Exenatide a Noninsulin Addition for Patients Failing Basal Insulin
Exenatide twice daily shows similar glycemic control with weight loss and less hypoglycemia as compared to mealtime insulin… Some patients with advanced type 2 diabetes still do not achieve glycemic control with insulin glargine and metformin. Mealtime insulin lispro is often added on to the regimen but it is associated …
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