Glucose regulation and weight management are very important factors when treating type 2 diabetes patients… Prior studies have shown that glucagon-like peptide receptor agonist are beneficial not only for better glucose control but also helpful in weight reduction in patients with type 2 diabetes. Other studies and recommendations on type …
Read More »Severe and Nonsevere Hypoglycemia in Glargine Insulin Treatment
Hypoglycemia was relatively uncommon in the ORIGIN (Outcome Reduction with an Initial Glargine Intervention) trial… ORIGIN trial investigators have published results of their look at treatment with insulin glargine compared with standard care early in the course of dysglycemia, and its effects on hypoglycemia. A total of 12,537 people with …
Read More »New Insulin Glargine 300 Effective in Type 1 Diabetes
Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …
Read More »Sulfonylureas, Insulin, and Metformin Cancer Risks for Patients with Type 2 Diabetes
Can metformin reduce the risk of cancer for those with type 2 diabetes?… In previous studies, metformin has been shown to decrease the risk of cancer in type 2 diabetes. A recent meta-analysis showed a 34% reduction in the incidence of any cancer and a 33% reduction in cancer mortality; …
Read More »High Calorie Consumption after GDM Leads to Increased Insulin Resistance in Hispanic Women
The women also experienced reduced beta cell function…. Researchers from the University of Southern California, Los Angeles, assessed associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM …
Read More »t:flex Insulin Pump Cleared by FDA
The t:flex Pump is designed for patients who require more than 100 units of U-100 insulin per day, such as teenagers with type 1 diabetes and many people with type 2 diabetes. The pump offers the benefits of pump therapy without the frequent reservoir changes required by 200- and …
Read More »Patients with Type 1 Diabetes Can Still Produce Insulin 40 Years Later
According to a new study, about 1/3 of people with type 1 diabetes produce insulin, as measured by C-peptide, even upward of 40 years from initial diagnosis… The findings shed new light on the long-accepted belief that patients with type 1 diabetes lose all ability to produce any insulin. The …
Read More »Fasting Insulin Levels in Children May Predict Adult Diabetes
Elevated fasting insulin levels in children aged 3 to 6 years may help predict which children will develop type 2 diabetes as adults… Although researchers did not find the same association for older children and adolescents, they did find an association between body mass index (BMI) in peripubertal years and …
Read More »Vibe Insulin Pump with CGMS Technology
Animas, a division of Johnson & Johnson, has finally won FDA approval for its Vibe insulin pump and continuous glucose monitoring system. The pump is the first to pair with Dexcom’s G4 PLATINUM continuous glucose monitor that samples interstitial fluid every five minutes and provides a trending chart of …
Read More »Increased Mortality with Combining Sulfonylurea and Insulin
About 11,000 patients using both insulin and sulfonylurea were evaluated… Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the differences in outcomes of treatment combinations. Outcome …
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