A new study found enterovirus infection increased the risk of type 1 diabetes in children… Doctors in Taiwan have found evidence that links enterovirus infection or EV (poliovirus, Coxsackievirus A and B, echovirus) and type 1 diabetes in children. Previous studies have shown an association between EV infection and type …
Read More »Antibiotic Use by Age 2 Associated with Obesity Risk
Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity… Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity say researchers from The Children’s Hospital of Philadelphia in a retrospective study based on …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #15: Diabetic Nephropathy
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Diabetic nephropathy is a clinical diagnosis based upon the detection of proteinuria in a patient with diabetes in the absence of another obvious cause such as infection. Many of these patients will also be hypertensive, have retinopathy and, in advanced stages, renal …
Read More »Fried Food and Risk for Gestational Diabetes
Frequent consumption of fried foods pre-pregnancy increases a woman’s risk for gestational diabetes… Gestational diabetes mellitus is not just a short-term perinatal outcome, but also long-term health complications in both the mothers and baby. The significance of diet and lifestyle is important in the prevention of gestational diabetes mellitus in …
Read More »Light Technology May Be Used to Control Type 2 Diabetes
Use of blue LED light activates sulfonylureas… The use of sulfonylureas has long been an option for controlling type 2 diabetes. Their use is often associated with hypoglycemia and weight gain. A new technology seeks to minimize these side effects. Researchers are looking at a prototype sulfonylurea, JB253, which stimulates …
Read More »Blocking a Genetic Variant Associated with Type 2 Diabetes May Improve Insulin Secretion
Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …
Read More »AAAHC Releases Obesity Management Patient Toolkit
AAAHC Releases Obesity Management Patient Toolkit The Accreditation Association for Ambulatory Health Care has released a toolkit for obesity management, Disease Management: Obesity in Adults. The tool is intended to empower medical professionals to discuss obesity management with their patients and includes a discussion of treatment options, as …
Read More »Vitamin D and Type 2 Diabetes Risk
In an analysis using genetic data from over 25 different studies involving diabetes patients, researchers can find no causal association between higher vitamin D levels and lower diabetes risk… Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, have been associated with an increased risk of …
Read More »Could a Lower Dose of Otelixizumab Preserve Beta-cell Function in Type 1?
Previous studies used higher doses of otelixizumab, an anti-CD3 monoclonal antibody, but also saw a reactivation of the Epstein Barr virus…. In patients with type 1 diabetes, a higher C-peptide concentration is associated with a controlled HbA1c and fewer complications. Otelixizumab is an anti-CD3 monoclonal antibody that works by …
Read More »Longer Working Hours Associated with Higher Type 2 Incidence
Socioeconomic status plays a role in how strong the association is…. Previous studies have shown an association between working longer hours and risk factors that can contribute to type 2 diabetes incidence. These risk factors included physical inactivity, unhealthy lifestyle, poor nutritional choices, and cardiovascular disease. Other studies have …
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