Mr. Huang manages his diabetes with his lifestyle modifications, metformin, and linagliptin, and returns every 6 months for follow-up visits. Three years after initiating this treatment plan, he returns to your clinic for his 6-month check-up. When asked how his diabetes management is going at home, he shares that recently he has been “unable to really get out and get as much exercise as he knows he should due to his creaky, old knees acting up.” His current office A1C is 8.8%. You discuss with him what the next management steps may be to achieve his individualized glycemic goal. What would your next medical management step be? A. Add a rapid-acting insulin analogue B. Add a long-acting insulin analogue C. Add a GLP-1 agonist D. Add a sulfonylurea Follow the link for the answer.

In this week's Homerun Slides, the benefits of health and disease management programs, which can integrate evidence-based best practices into patient care.

The natural history of T2DM has been well described in multiple populations and is reviewed in references [1] and [3]. Individuals destined to develop T2DM inherit a set of genes from their parents that make their tissues resistant to insulin and the insulin resistance is aggravated by weight gain and physical inactivity. Hepatic insulin resistance is manifested by an overproduction of glucose during the basal state despite the presence of fasting hyperinsulinemia [38] and an impaired suppression of hepatic glucose production (HGP)

The different mechanisms of action of these two drugs make them an excellent combination in the treatment of patients with type 2 diabetes mellitus (T2DM).

Investigation into the effect of surgery, from mortality to length of hospital stay, on patients who have diabetes with consistently high blood glucose.

Mini-dose glucagon might be a better option for treating exercise-induced hypoglycemia than carbohydrate ingestion or insulin dose reduction.

Study reveals how implementing occupational therapy strategies can help patients achieve glycemic goals.

Study describes patient characteristics that place patients with type 2 diabetes at increased risk for severe hypoglycemia.

Childhood overweight is associated with an increased risk of type 2 diabetes in adulthood.

You are concerned about Mr. Carlson’s cigarette use because cigarette smoking has been shown to have multiple physiological impacts on health. Which one of the following statements regarding smoking and type 2 diabetes is true? A. It equally affects all-cause mortality in individuals with and without diabetes B. In individuals with diabetes, it causes more rapid progression to micro- and macroalbuminuria C. It has not been linked to worsening glycemic control D. The use of bupropion in contraindicated in diabetes Follow the link to see the answer,