David Levy, MD, FRCP      Mononeuropathies and other focal syndromes Peripheral mononeuropathies Upper limb Carpal tunnel syndrome (median nerve) Carpal tunnel syndrome is very common (remember the association with primary hypothyroidism, especially in type 1 diabetes) and may present with atypical symptoms, as it is often superimposed on diabetic polyneuropathy. Consider it …

David Levy, MD, FRCP      Charcot neuroarthropathy Charcot neuroarthropathy is a serious and poorly understood condition associated with rapid destruction of bones and joints and resulting in bone fragmentation. It occurs only in patients with advanced sensory and autonomic neuropathy, and is characteristic of long-duration type 1 diabetes with other microvascular complications, …

David Levy, MD, FRCP      Foot ulceration The ulcerated, infected and possibly gangrenous foot is a common reason for hospital admission. Anatomically, diabetic foot ulceration is restricted to the region distal to the ankle; proximal lesions are more likely ischemic, vasculitic, venous, or to have another underlying cause. Most ulcers are predominantly …

David Levy, MD, FRCP      Introduction The devastating consequences of diabetic neuropathy are seen every day both in hospital – more bed days are taken up with the consequences of diabetic foot ulceration than any other diabetic complication – and in primary care, where sensory symptoms, especially pain, and autonomic neuropathy, especially …

Dr. Paolo Fiorina talks about the process of stem cell therapy and how the researchers have found a way to use a patient’s own bone marrow stem cells. This also prevents an autoimmune response attacking the cells. Dr. Fiorina discusses how he would like to start fully testing this new …

Dr. Paolo Fiorina explains how, after 30 years of research into the potential of stem cell therapy and immunotherapy for curing type 1 diabetes, new developments in these fields are offering genuine hope for the first time. In a recent study with about 60 type 1 patients, significant progress was …

Firas El-Khatib, PhD, explains some of the details of how the current bionic pancreas works – with three devices – and how a future design will probably only have two devices with a combination insulin/glucagon pump system. He says that, although the bionic device is not a cure, it is …

Firas El-Khatib, PhD, gives us a short introduction to himself and then explains some of his work developing the bionic pancreas focusing especially on the challenges of developing an algorithm. He also discusses the very positive results of the most recent study where patients were able to fully utilize the …

JDRF-funded studies on development of artificial pancreas, encapsulated islet cell therapies, and kidney preservation presented at 2015 ADA Scientific Sessions.

New analysis suggests either aerobics or strength training can improve blood sugar levels, lower body fat and waist size, more… In a randomized trial, researchers at the University of Texas Southwestern Medical Center at Dallas compared different strategies of exercise for people with type 2 diabetes. They found that people …