Treatment with canagliflozin, an SGLT-2 inhibitor, was associated with reductions in body weight, HbA1c and systolic blood pressure.
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Active Children Are Less Prone to Obesity as Teens
Inactivity seems to compromise the cardiometabolic system…. The study with 4,600 children found that children who engage in daily physical exercise reap the health benefits as early as their teens. They found that those who were more active in late childhood had a lower body weight and lower risk factors for …
Read More »FDA Panel Favors Approval of Alirocumab for Hypercholesterolemia
The FDA’s Endocrinologic and Metabolic Advisory Committee has recommended approval of the first PCSK9 inhibitor alirocumab (Praluent, Regeneron and Sanofi) injection for treatment of hypercholesterolemia. In a 13-3 vote, the panel decided that the LDL-lowering benefit of alirocumab outweighed the risks in one or more patient populations. The committee based …
Read More »First CVD Trial of a GLP-1 Agonist Finds No Cardiac Risk or Benefit
The Evaluation of Lixisenatide in Acute Coronary Syndrome (ELIXA) study also found a modest benefit for weight control, and no increase of risk for hypoglycemia or pancreatic injury. There was no increased risk for cardiovascular death, heart attack, stroke, unstable angina or heart failure in people with type 2 diabetes. …
Read More »Predicting Future Cardiovascular Events By Missing Teeth
Advanced tooth loss can often indicate that a person has a history of inflammatory oral diseases. In an extensive cohort study, carried out by the University of Helsinki (Finland) in collaboration with The National Institute for Health and Welfare (THL), an association was found between tooth loss and future cardiovascular …
Read More »FDA Panel Favors Approval of Alirocumab and Evolocumab for Hypercholesterolemia
FDA Panel Favors Approval of Alirocumab and Evolocumab for Hypercholesterolemia. Two PCSK9 inhibitors have been recommended for approval. The agency will likely follow the advisory committee’s advice when it decides whether to approve the drugs, alirocumab (Praluent) from Sanofi SA and Regeneron Pharmaceuticals Inc., and evolocumab (Repatha) from Amgen Inc., for …
Read More »Letter from the Editor, #785
One of the best things that happens at the ADA is the chance to interact with our Advisory Board members. When Steve and I started this publication 15 years ago, we were able to win readers with our unique style of presenting the news. Along the way we have become …
Read More »All My Food Facts
FoodFacts, Inc. Free for a Limited Time/iOS For your patients with weight issues, food allergies, and other health issues not normally covered in food information apps, this app takes dietary concerns a step further. Included in the app are features tracking: Diet, Ailment, Allergy, Ingredient and Nutrition Tracker, Calorie Counter, Food …
Read More »Etta Vinik: Making Patients Feel Important and Dancing with Diabetes
Etta Vinik talks about how clinicians need to understand how patients sometimes have to go to incredible efforts just to get in for an appointment and that it is important to spend time with them when they do. And she lets us know how finding a good physical activity that …
Read More »Etta Vinik: The Importance of Learning to Listen to Patients
While we are pulling together this past weekend’s ADA videos for you, we thought we’d share this video from last year’s ADA with Etta Vinik, who has partnered with her husband Aaron Vinik, MD, over many years in improving diabetes education for patients as well as helping cliinicians to better …
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