If you get diabetes when you are 60 years old, the odds of developing kidney disease in your lifetime is low. However, if you are diagnosed when you are in your 30s or 40s, the risk is increased, and the likelihood of needing dialysis is greatly increased. This week, we …

This week we have the second part of our two-art interview with Dr. Janice Smiell, CMO at Alliqua BioMedical, Inc. Dr. Smiell, and we delve a little deeper into the specifics of this new technology to heal chronic wounds using placental biomaterials. Steve Freed: With all the testing that is …

The drug reps for DPP-4 inhibitors, GLP-1 agonists, and various insulins have been having a field day talking to prescribers about the possible cardiovascular effects of SGLT-2 inhibitors. This along with the relatively small risk of UTI’s has possibly caused some of our readers to shy away from the whole …

Researchers at McGill University Health Centre, Montreal, Canada, report that metformin has some biochemical properties effects that would suggest a benefit in treating chronic liver diseases. They searched the PubMed and Ovid MEDLINE databases from 2000 to March 2015, but were unable to find any evidence pointing to an independent …

In a 12-year study with over 50 generations, rats who had undernourished ancestors were found to be more susceptible to diabetes and other metabolic diseases… The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today’s changing environment. New …

The way that type 2 diabetics respond to initial treatment could predict the long term effectiveness of their treatment regimen… There are a variety of treatment options for type 2 diabetics, with no clear reason why some drugs work better than others in some individuals. That is why diabetes treatment …

Scores of the diabetes patients decreased by an additional 12 percent during the two-year period… Type 2 diabetes is known to put individuals at risk for numerous health complications. Now a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) sheds new light on the often overlooked toll …

Binge-eating cavefish share mutated gene with some obese people. Blind cavefish have evolved to be starvation resistant, constantly hungry, and fat but healthy. New research shows they share genetic mutations with some obese people. Narration by study co-author Nicolas Rohner. Blind cavefish that have adapted to annual cycles of starvation …

Investigators are targeting individualized diabetes therapy using the genetic approach… Dr. Lazar and his team focused on a fat molecule called PPARγ, which is also the target for the thiazolidinedione (TZD) class of drugs. PPARγ binds to DNA and activates the expression of other genes. The researchers hypothesized that genetic …

Oxidized LDL (oxLDL) cholesterol and fructosamine are associated with severe heart disease in women…. Insulin resistance is known to increase risk for cardiovascular diseases. However some patients with insulin resistance appear to experience only moderate symptoms of coronary blockage while others suffer severe coronary atherosclerotic and continue to progress after …