Diabetic patients can lose weight with medication specific for weight loss... In two randomized, double-blind and placebo-controlled studies, the safety and efficacy of treatment with phentermine (PHEN) and topiramate ER (TPM ER) (Qsymia) plus lifestyle for weight loss and glycemic benefits were measured. The studies included obese/overweight adults with type 2 diabetes. …
Read More »Can Automated Internet Based Weight-Loss Programs Work?
Subjects who participated in an automated internet structured behavioral treatment program showed better weight losses…
Read More »Beloranib Demonstrates Weight Loss in Hypothalamic Injury-Associated Obesity
The drug, a first-in-class MetAP2 inhibitor, was well-tolerated and also improved cardiovascular disease risk factors… Zafgen has announced that ZAF-221, a randomized, double-blind, placebo-controlled Phase 2 clinical trial of beloranib, a MetAP2 inhibitor, in 14 adults with hypothalamic injury associated obesity, or HIAO, met the primary efficacy endpoint of weight …
Read More »t:flex Insulin Pump Cleared by FDA
The t:flex Pump is designed for patients who require more than 100 units of U-100 insulin per day, such as teenagers with type 1 diabetes and many people with type 2 diabetes. The pump offers the benefits of pump therapy without the frequent reservoir changes required by 200- and …
Read More »Diabetes Mellitus 101 for Cardiologists, Part 14
In this week’s Homerun Slides, we focus in on the specifics of the drug, Ranolazine, which is used to treat angina, and its effects on patients with diabetes… To download these slides in PowerPoint (.ppt) format, use this link: Diabetes Mellitus 101 for Cardiologists, Part 14 Other sets in this series: Diabetes Mellitus …
Read More »Dr. Timothy Garvey on Qsymia and Other New Therapies for Weight Loss
Steve Freed: Let’s start out with a little background about Qsymia and Belviq. What is the FDA allowing you to treat with the drugs? Dr. Timothy Garvey: In 2012, the FDA approved two new weight loss medications. In 2014, another medication was approved. That is three new medications. We hope …
Read More »Hypoglycemia Can Impact Job Performance
A 55-year-old woman with type 2 diabetes who was being treated with glimiperide had had a difficult time finding a job. She was finally hired into a law firm as a legal secretary. She would be frequently called into meetings at the last minute, often late mornings and afternoons, right …
Read More »Handbook of Diabetes, 4th Ed., Excerpt #26: Pregnancy and Diabetes
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Pregestational diabetes is the most common medical problem that complicates pregnancy, affecting 1 in 264 births (0.38%) in the UK in 2002–3, with over 25% occurring in women with type 2 diabetes. The Kaiser Permanente database recorded an average rate of 1.3% …
Read More »Mortality Rates for Type 1 Diabetes Patients Still Too High
Despite major advances in the treatment of type 1 diabetes over the past 30 years, type 1 men are living approximately 11 fewer years than their non-diabetic peers. For women, the years lost is even higher at 13…. Scottish researchers examined data from a prospective cohort of patients in Scotland …
Read More »Intensive Therapy Lowers All-cause Mortality Rates for Type 1’s
An examination of 27 years of follow-up data from the EDIC study reveals that intensive glycemic therapy was associated with a modestly lower all-cause mortality rate…. After the DCCT (1983-1993) ended, participants were followed up in a multisite (27 US and Canadian academic clinical centers) observational study (Epidemiology of Diabetes …
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