An international team of researchers examined a cohort of nearly 50,000 patients to find out…. Dipeptidyl peptidase-4 (DPP-4) inhibitors may alter the immune response and increase the risk of infections, but evidence for this association is limited. The United Kingdom Clinical Practice Research Datalink (CPRD) and the Hospital Episodes Statistics …
Read More »Type 2 Diabetes Remission Very Rare in Non-Bariatric Surgery Patients
American researchers looked at data on over 120,000 type 2 patients to find out what rates of remission were…. Previous studies have shown that bariatric surgery can result in long-term weight loss, improvement in cardiovascular risk factors, and a reduction in mortality rate of 15% from baseline. However, in a …
Read More »Obesity and CHD Association in Type 2 Diabetes Patients
Are obesity and CHD truly associated?… Researchers from the U.S. and China examined data on 30,434 diabetic patients from the Louisiana State University Hospital-Based Longitudinal Study (10,955 men and 19,479 women). Patients included were 30-95 years of age without a history of CHD or stroke in the Louisiana State University …
Read More »Genetic Variations Associated with Traits Underlying Type 2 Diabetes in Mexican-Americans
But narrowing down the exact genes responsible proves to be complicated… While people of Mexican ancestry are nearly twice as likely to develop type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin. In an effort to understand …
Read More »Glargine vs. Liraglutide in Poorly Controlled Type 2 Diabetes Treatment
Both medications lowered HbA1c and both groups of patients lost weight…. This randomized, multinational, open-label trial included subjects treated for T2DM with metformin ± sulphonylurea, who had glycated haemoglobin (HbA1c) levels of 7.5–12%. Subjects were assigned to 24 weeks of insulin glargine, titrated to target fasting plasma glucose of 4.0–5.5 mmol/L or liraglutide, escalated …
Read More »Linagliptin/Metformin Combination vs Linagliptin Monotherapy for Type 2 Diabetes
Earlier treatment for poorly controlled type 2 diabetes patients is advocated… Researchers from the University of Calgary, Alberta, Canada, evaluated glucose-lowering treatment strategies with linagliptin and metformin in people with newly diagnosed type 2 diabetes and marked hyperglycemia, a prevalent population for which few dedicated studies of oral antidiabetes drugs …
Read More »Dexcom G4 Platinum with SHARE Gets FDA Approval
The FDA has approved Dexcom’s G4 PLATINUM Continuous Glucose Monitoring System with Share. The Dexcom Share receiver uses a secure wireless connection via Bluetooth Low Energy (BLE) between a patient’s receiver and an app on the patient’s smartphone to transmit glucose information to apps on the mobile devices of …
Read More »Barbara E. Corkey, PhD, Introduction: The Unknown Causes of Diabetes and Obesity
Dr. Barbara E. Corkey introduces herself and explains a little about the work she and her team do in her lab, examining the effects of various substances, both nutritional and non-food substances, on the human cell…. More videos with Dr. Corkey: Introduction: The Unknown Causes of Diabetes and Obesity What …
Read More »Barbara E. Corkey, PhD: What Environmental Substances May Cause Diabetes?
Dr. Barbara E. Corkey talks about how many new plastics haven’t really been tested for their potential effects on the human body, including causing obesity and/or diabetes. She also mentions other substances including fire retardants and pesticides that are likewise not fully tested, and advocates for more testing of these …
Read More »Barbara E. Corkey, PhD: Why Food and Packaging Industry Should Collaborate More Closely with Researchers
Dr. Barbara E. Corkey talks about a few of the 5,000 substances that haven’t really been studied for their effects of obesity and urges more collaboration between researchers in academia and the food and packaging industries. More videos with Dr. Corkey: Introduction: The Unknown Causes of Diabetes and Obesity What …
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