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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #38: Normal Beta-cell Function Part 3 of 6

Beta-Cell response to nonglucose secretagogues: Proteins and amino acids -- The insulinotropic effect of oral proteins was first described almost 50 years ago and recently confirmed. After the ingestion of a small amount of proteins (30–50 g) or a larger amount of proteins (2 g kg−1), plasma insulin was raised two- to threefold over baseline and remained persistently elevated for 90 or 240 minutes, respectively. In either case, blood glucose did not change, whereas both GLP-1 and GIP levels were raised threefold over fasting values.

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Lantus Biosimilar

When the Biosimilar insulin to Lantus becomes available for about 10-15% less cost, will you recommend it to your patients? Follow the link to share your opinion!

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Question #847

Test Your Knowledge

Weight loss has been shown to have a positive impact on glucose control and cardiovascular risk factors. At which weight loss threshold do these positive benefits start to become meaningfully apparent? A) Weight reduction of 0-4% B) Weight reduction of 5-10% C) Weight reduction of 11-15% D) Weight reduction of 16-20% Did you get it right? Follow the link to find out!

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