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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #67: Regulation of Glucose Metabolism in Liver Part 3 of 11

Regulation of glycogenolysis: Glycogen metabolism is regulated by reciprocal changes in the activities of glycogen synthase and glycogen phosphorylase. Net glucose production from glycogen occurs when phosphorylase activity is higher than synthase activity. Activation of glycogen phosphorylase is the culmination of a “glycogenolytic cascade” that is initiated by the binding of glucagon or beta-adrenergic agonists to their receptors in liver cells.

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Question #877

Test Your Knowledge

In a survey with medical professionals, 78% got this wrong. Can you do better? According to the Centers for Disease Control and Prevention, what percentage of patients who have diabetes and are older than 65 y will die of heart disease? A. 58% B. 68% C. 78% D. 88% Follow the link to see if you got the right answer!

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