Daily weight changes may motivate individuals to maintain a healthier lifestyle…
Read More »Heart Failure Complication in Type 2 Diabetes Focus of Study
Risk of hospitalization, early death doubled in type 2 patients… Cardiovascular complications have been linked to diabetes. However, according Dr. Timothy Davis from University of Western Australia, “there have been no detailed contemporary population-based studies of heart failure (HF) complicating type 2 diabetes.” In an effort to investigate predictors and …
Read More »Risk of Early Death Tied to Episodes of Diabetic Ketoacidosis
Type 1 diabetes patients had a 30% higher risk of dying within six years after more than four hospitalizations for diabetic ketoacidosis…
Read More »Second Tuberculosis Vaccine Treatment for Type 1 Diabetes Underway
A clinical trial to investigate whether repeated injections of the tuberculosis vaccine bacille Calmette-Guérin holds promise… The researchers announced the start of their phase 2 trial at the American Diabetes Association (ADA) 75th Scientific Sessions in Boston. Study author Denise Faustman, MD, director of the immunobiology laboratory at Massachusetts General …
Read More »TECOS Trial: No CVD Risks or Heart Failure with Sitagliptin in High-Risk Diabetic Patients
No significant difference in incidence of infections, cancer, renal failure, or severe hypoglycemia… In patients with type 2 diabetes and cardiovascular disease, the use of sitagliptin (Januvia, Merck), a dipeptidyl peptidase-4 (DPP-4) inhibitor used to lower HbA1c levels, is not associated with an increased risk of cardiovascular events, according to …
Read More »Triple Therapy Improves Glycemia in Type 1 Diabetes
Combination of insulin, a GLP-1 receptor agonist and an SGLT-2 inhibitor effective, includes DKA risk.
Read More »Partners and Spouses Have Double Diabetes Risk
Spouses or live-in partners of people newly diagnosed with diabetes twice as likely to develop diabetes…
Read More »Investigational Drug ITCA 650, a GLP-1 Receptor Agonist, on the Way
Drug shows a significant reduction in HbA1c in patients with type 2 diabetes… A new investigational drug is underway to help with reduction of HbA1c, weight, and improve glycemic control in type 2 diabetes patients. ITCA 650 is an injection-free GLP-1 receptor agonist that provides continuous subcutaneous exenatide for 12 …
Read More »Lilly Insulin: A Better Alternative than Lantus?
Peglispro allows slow insulin absorption, but associated with injection site reaction and increased ALT and triglycerides… Peglispro or pegylated lispro insulin is currently under phase III investigation for both type 1 and type 2 diabetes. The large hydrodynamic size of peglispro allows slow insulin absorption and reduces clearance, resulting in …
Read More »No Association Between Sulfonylurea Use and Cardiovascular Mortality
Sulfonylureas not associated with increased cardiovascular mortality, myocardial infarction and stroke in a meta-analysis of 47 randomized clinical trials… Sulfonylureas are relatively inexpensive and are important therapeutic agents in type 2 diabetes management. However, they are not widely used due to safety concerns regarding hypoglycemia and weight gain. Furthermore, it …
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