The two new injectable drugs, alirocumab and evolocumub, have been recommended for FDA approval by the agency’s Endocrinologic and Metabolic Advisory Committee.…
Read More »Using LixiLan Does Not Increase Hypoglycemia
Fixed-dose insulin glargine/lixisenatide improves HbA1c levels in patients with type 2 diabetes…
Read More »Dulaglutide over Insulin Glargine in the Reduction of HbA1c?
GLP-1 analog also showed reduction in weight and incidence of hypoglycemia… Dulaglutide (Trulicity) is a glucagon-like peptide analog that is used once weekly to improve blood glucose level. During the open-label, multinational, parallel arm study, researchers compared the safety and efficacy of dulaglutide 0.75mg and 1.5mg to insulin glargine in …
Read More »Blood Biomarkers May Predict Risk of Severe Hypoglycemia
C-peptide and islet autoantibodies may serve as biomarkers to predict the risk of severe hypo’s during intensification of type 2 diabetes treatment….
Read More »Physical Activity During Pregnancy Reduces Gestational Diabetes Risk 30%
Those women who continued to exercise throughout their pregnancy achieved an even higher risk reduction… Gestational diabetes and excessive maternal weight gain are associated with many negative outcomes for both the mother and the baby including: pre-eclampsia, hypertension and preterm birth. Expectant mothers who are diagnosed with gestational diabetes are …
Read More »Early Detection of Type 2 Diabetes Reduces Death Caused by Cardiovascular Disease
Early detection and treatment of type 2 diabetes may be more beneficial than aggressive control of blood glucose, blood pressure and cholesterol… Screening to identify type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research that combined large scale clinical observations and innovative …
Read More »Skin Bacteria a Cause of Diabetes?
Toxin produced by Staphylococcus aureus (S. aureus), a common skin bacteria, caused glucose intolerance in rabbit cells… Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers …
Read More »A Dual SGLT1/SGLT2 Inhibitor Can be a Treatment Option in Type 1 Diabetics
Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, is a promising option as adjunct therapy for type 1 diabetes patients… In a randomized double blind phase 2 study, 33 type 1 diabetic patients were treated with either sotagliflozin or placebo. Researchers assessed safety, glycemic control, bolus insulin dose reduction which was …
Read More »When Should You Refer Your Patients to a Certified Diabetes Educator?
American Diabetes Association (ADA), American Association of Diabetes Educators (AADE) and the Academy of Nutrition and Dietetics (AND) joint position statement…. There are four times the need for diabetes self-management education and support should be assessed: at diagnosis, annually, when there are new complications and during transitions of care. Research …
Read More »Tight Blood Glucose Control and Cardiovascular Disease
How low should we go? A new study is a 10-year follow-up to the Veterans Affairs Diabetes Trial in which 1,791 type 2 diabetics over the age of 60 were enrolled. The veterans were randomly placed in either the “standard” therapy group that had a higher HbA1c goal or the …
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