Insulin Therapy Center

Adding an SGLT2 inhibitor to multiple daily doses of insulin improved glycemic control, benefited weight loss, lowered insulin doses, and no increase in hypoglycemia was seen…   Some patients with inadequately controlled type 2 diabetes still do not achieve glycemic control with multiple daily doses of insulin. Empagliflozin is a …

Typically when we diagnose a type 2 patient we start on the normal pathway of metformin and “diet and exercise” modifications. For many of our patients this regimen makes a significant improvement in their glucose levels and A1c values…. But for those patients who don’t improve, we are then forced …

Dulaglutide shows efficacy in diabetes patients with poor glycemic control already taking multiple oral medications…. Patients with uncontrolled diabetes already taking multiple oral agents often require insulin therapy for better glycemic control but insulin therapy is associated with hypoglycemia and weight gain. Dulaglutide, approved by the FDA in September 2014, …

For people with type 1 diabetes, long-acting insulin may be a better treatment choice than intermediate-acting insulin…. Different types of insulin are used to manage type 1 diabetes with insulin injections. Long-acting insulin takes about one hour to begin lowering blood sugar levels and lasts up to 26 hours, while intermediate-acting …

Insulin-dependent diabetes patients were at an increased risk of post-surgery complications following lumbar fusion including death, sepsis, wound infection and 30-day readmission…. Patients with insulin-dependent diabetes mellitus (IDDM) have an increased risk of a number of postoperative complications after lumbar fusion compared with those who have noninsulin-dependent diabetes mellitus (NIDDM) …

And fatal cardiovascular disease risk is 43% lower for type 1 diabetes patients using insulin pumps over multiple daily injections….  Dr. Gudbjörnsdottir and colleagues in Sweden conducted an observational study using patient data from the Swedish National Diabetes Registry from 1996 till 2014. The data included more than 95% of …

Higher levels of hypothalamic nitric oxide could lead to less insulin clearance and more lipogenesis…. Nitric oxide (NO) is an important neurotransmitter produced in the paraventricular nucleus (PVN) of the hypothalamus. Previous studies suggested that the level of NO was inversely correlated with systemic insulin clearance. However, little is known …

I was reviewing a client’s insulin administration. She was administering Levemir (insulin detemir), 60 units, with a FlexPen. She said that she just dialed the dose to the maximum it would allow her as she knew it only would dial to 60 units. She did not confirm the dose visually. Although …

Using a GLP-1 agonist with insulin may be the most effective therapy combination for lowering HbA1c in type 2 diabetes patients…. Researchers performed a systematic review and pooled meta-analysis of randomized controlled trials published between January 1, 1950 and July 29, 2014. Out of the 2,905 studies that were identified, …

Tresiba, in combination with insulin aspart, effectively improved long-term glycemic control….