SGLT-2 inhibitor use in the management of glucose in type 2 diabetes could reduce blood pressure in patients with hypertension…. In a new study, researchers found that empagliflozin lowered blood pressure in patients with type 2 diabetes and hypertension. Hypertension affects about two-thirds of patients with diabetes. See more …
Read More »Potential of SGLT2 Inhibitors in Type 1 Diabetes
Pilot study shows that an SGLT-2 inhibitor doses of 5-mg and 10-mg were associated with significant reductions in blood glucose and total daily insulin dose…. Dapagliflozin is a member of the SGLT2 inhibitor class of diabetic medications indicated only for treatment of type 2 diabetes. Dapagliflozin helps reduce blood glucose …
Read More »Glucotoxicity and Lipotoxicity: Reasons for Use of Insulin in Type 2 Patients
Typically when we diagnose a type 2 patient we start on the normal pathway of metformin and “diet and exercise” modifications. For many of our patients this regimen makes a significant improvement in their glucose levels and A1c values…. But for those patients who don’t improve, we are then forced …
Read More »GLP-1 Receptor Agonist a Treatment Option in Type 2 Patients with Renal Insufficiency
Phase 3 trial demonstrates the safety and efficacy of albiglutide in type 2 diabetes patients with renal impairment…. Renal impairment is a common comorbid condition in type 2 diabetes patients with reported incidence rates as high as 35%. Those with renal insufficiency often find their diabetes treatment options limited. Possible …
Read More »Low Carb Diet Improves Quality of Life for Type 2 Diabetes Patients
Type 2 diabetes patients on a low-carb diet had improvements in physical function, pain reduction, and overall health after 12 months….
Read More »Two Positive Phase 3 Trials for ITCA 650, a GLP-1 Agonist, in Type 2 Diabetes
FREEDOM-1 and FREEDOM-1 High Baseline (HBL) study showed positive results when the continuous subcutaneous infusion of exenatide is added to standard oral diabetes medications…. ITCA 650 is a continuous subcutaneous infusion of exenatide through a pump for the treatment of type 2 diabetes. FREEDOM-1 is a double blinded, randomized, placebo-controlled, multicenter, phase …
Read More »Best Insulin Regimen for Type 1’s
For people with type 1 diabetes, long-acting insulin may be a better treatment choice than intermediate-acting insulin…. Different types of insulin are used to manage type 1 diabetes with insulin injections. Long-acting insulin takes about one hour to begin lowering blood sugar levels and lasts up to 26 hours, while intermediate-acting …
Read More »Gout Linked to Increased Type 2 Diabetes Risk
Gout appears to increase the risk of type 2 diabetes, especially in women…. Researchers followed more than 35,000 gout sufferers in the United Kingdom and found that women with gout were 71 percent more likely to develop diabetes compared with people without gout. For men, the increased risk was 22 …
Read More »Study of Identical Twins Reveals Type 2 Diabetes Clues
By studying identical twins, researchers have identified mechanisms that could be behind the development of type 2 diabetes…. The study involved 14 pairs of identical twins in Sweden and Denmark. One of each twin had type 2 diabetes while the other was healthy. Emma Nilsson, the researcher who carried out …
Read More »EASD: Non-albuminuric CKD in Type 1 Diabetes Patients Increasing
Researchers are unsure why the phenotype is increasing but suggest that more effective treatments may be contributing to the increase in non-albuminuric CKD…. Chronic kidney disease (CKD) is a common complication of diabetes associated with glomerular filtration rate (GFR) loss. Normally, before the GFR loss occurs, albuminuria will be detected. …
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