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Handbook of Diabetes, 4th Edition, Excerpt #5: Epidemiology and aetiology of type 1 diabetes

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  Rudy Bilous MD, FRCP Richard Donnelly MD, PHD, FRCP, FRACP   The most common cause of type 1 diabetes (over 90% of cases) is T cell-mediated autoimmune destruction of the islet beta cells leading to a failure of insulin production. The exact aetiology is complex and still imperfectly understood. However, it …

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