Conditions

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Diabetic nephropathy is a clinical diagnosis based upon the detection of proteinuria in a patient with diabetes in the absence of another obvious cause such as infection. Many of these patients will also be hypertensive, have retinopathy and, in advanced stages, renal …

Frequent consumption of fried foods pre-pregnancy increases a woman’s risk for gestational diabetes… Gestational diabetes mellitus is not just a short-term perinatal outcome, but also long-term health complications in both the mothers and baby. The significance of diet and lifestyle is important in the prevention of gestational diabetes mellitus in …

Use of blue LED light activates sulfonylureas… The use of sulfonylureas has long been an option for controlling type 2 diabetes. Their use is often associated with hypoglycemia and weight gain. A new technology seeks to minimize these side effects. Researchers are looking at a prototype sulfonylurea, JB253, which stimulates …

Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …

  AAAHC Releases Obesity Management Patient Toolkit   The Accreditation Association for Ambulatory Health Care has released a toolkit for obesity management, Disease Management: Obesity in Adults. The tool is intended to empower medical professionals to discuss obesity management with their patients and includes a discussion of treatment options, as …

In an analysis using genetic data from over 25 different studies involving diabetes patients, researchers can find no causal association between higher vitamin D levels and lower diabetes risk… Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, have been associated with an increased risk of …

Previous studies used higher doses of otelixizumab, an anti-CD3 monoclonal antibody, but also saw a reactivation of the Epstein Barr virus….   In patients with type 1 diabetes, a higher C-peptide concentration is associated with a controlled HbA1c and fewer complications. Otelixizumab is an anti-CD3 monoclonal antibody that works by …

  Socioeconomic status plays a role in how strong the association is…. Previous studies have shown an association between working longer hours and risk factors that can contribute to type 2 diabetes incidence. These risk factors included physical inactivity, unhealthy lifestyle, poor nutritional choices, and cardiovascular disease. Other studies have …

  Maternal weight gain is key to controlling infant birth weight…. Infants born to mothers with pregestational diabetes are more likely to experience adverse outcomes, especially an increased birth weight. Previous studies have shown the importance of strict maternal glycemic control to prevent fetal hyperinsulinemia and accelerated growth. Excessive gestational …

  Adherence to healthy lifestyle during pregnancy is associated with a lower risk of gestational diabetes…. In a prospective cohort study, researchers looked at data on 14,437 women who participated in the Nurses’ Health Study II. Data was collected from the years of 1989-2001. Participants were aged 24 to 44 …