Heritability of T2DM: It has long been clear that T2DM clusters in families and it is well established that the risk of developing T2DM depends on both genetic and environmental factors. However, the exact proportion of the two, that is, the heritability, is difficult to determine and heritability estimates therefore vary in the range of 25–80% between studies. Twin-studies have estimated the genetic component by comparing disease concordance in dizygotic twins with concordance in monozygotic twins. In these studies probandwise concordance rates (number of affected twins having a diabetic co-twin) for monozygotic twins vary between 34 and 100%.
Read More »Production Assistant, Diabetes In Control
Diabetes and the Use of Complementary and Alternative Medicine
Herbal therapies and acupuncture among the most common alternative therapies used by patients with diabetes.
Read More »Patients With T2D, Mild Renal Impairment Can Benefit From A DPP-4 Inhibitor
Sitagliptin showed greater glycemic efficacy over dapagliflozin when added onto existing therapy.
Read More »Semaglutide Causes Weight Loss in Type 2 Diabetes Regardless of Baseline BMI
The SUSTAIN trials showed significant reductions in weight, but the true reason for the weight loss still unknown.
Read More »Overtreatment of Diabetes in Patients 75 Years or Older
Recent studies show one-quarter of the population over the age of 75 who have type 2 diabetes are tightly managed with medications and are high risk for hypoglycemia.
Read More »Dapagliflozin Improves Glycemic Index in Patients with T1DM but Increases Risk for DKA
SGLT shown as useful adjunctive agent when insulin monotherapy fails, but decrease in insulin use may prove harmful.
Read More »Lose Weight and Lose Type 2 Diabetes?
Scientists find dramatic weight loss may reverse type 2 diabetes in some patients.
Read More »Medication Compliance
Do you have a program in place to improve medication compliance? Follow the link to see how you and your colleagues compare.
Read More »Subjective Cognitive Decline
What proportion of Americans age 45 years and older have self-reported memory problems -- is it 1 in 30, 1 in 16, 1 in 9, or 1 in 4? Follow the link for the answer.
Read More »What NOT to Do When Your Patient is a Colleague
Health care professionals who are endocrinologists, cardiologists or who work in these specialized fields know the complications of prediabetes or diabetes. Many of us have these patients. Sometimes it’s almost natural to talk with these patients differently than we’d talk with most of our patients who aren’t as well-educated. A woman, 59 years of age with prediabetes and strong history of cardiovascular disease complained of a slight chest pain not associated with exertion or shortness of breath, just an ongoing discomfort. Other than this, the patient — who is herself a health care provider — is feeling fine.
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