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Production Assistant, Diabetes In Control

CGM Evaluation

What is most important when evaluating CGM?

A. Accurately evaluating glucose levels in the hypoglycemic range
B. Considering mean absolute relative differences in blood glucose (blood versus CGM value)
C. Considering patient-reported outcomes (positive experience and preference to or not to include CGM in their daily lives)
D. All of the above

Follow the link for the answer.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #141: The Genetics of Type 2 Diabetes Part 3

Identification of T2DM affecting genetic variants: The methods used to map disease-causing variation have evolved rapidly in the last decades thanks to technical advances in genotyping methods. Originally, disease-causing loci were identified primarily by linkage analysis, utilizing the long stretches of linkage in affected families. By genotyping 400–500 genetic markers, disease loci can be mapped on a genome-wide level without any prior hypothesis about which genes are involved. Finding that affected family members share a certain marker that is identical by descent (i.e., identical because it was inherited from the same parent) more often than expected by chance is evidence that a disease-causing variant is in linkage with that marker. This strategy has been very successful in mapping genetic diseases like MODY that have a strong penetrance and a known mode of inheritance.

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