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Tag Archives: Insulin therapy

The Return of C-Peptide: Why This Old Biomarker Is Finding New Clinical Uses

Healthcare professional reviewing C-peptide test results with a pancreatic model, blood sample, and glucose monitoring equipment representing beta-cell function assessment in diabetes care.

For many years, C-peptide testing was viewed as a simple tool to distinguish type 1 diabetes from type 2 diabetes. However, the story has changed. As researchers gain a better understanding of pancreatic beta-cell function, C-peptide testing in diabetes has become much more valuable than a diagnostic aid alone. Today, …

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Amylin Is Making a Comeback: Why This Forgotten Hormone Is Back in the Spotlight

Medical illustration showing amylin hormone activity alongside insulin therapy, highlighting next-generation amylin-based treatments for diabetes and obesity.

For years, glucagon-like peptide-1 (GLP-1) receptor agonists have dominated conversations about diabetes and obesity treatment. However, another hormone is quietly returning to the spotlight. Amylin diabetes therapy is making a comeback as researchers develop a new generation of drugs designed to improve blood glucose control and support weight management. Amylin …

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Could “Smart” Insulin End Hypoglycemia? The Race Toward Glucose-Responsive Therapy

Illustration of glucose-responsive insulin technology showing a smart insulin vial, syringe, blood glucose monitor, and molecular structures representing glucose-activated insulin therapy.

For more than a century, insulin has saved millions of lives. Yet despite remarkable advances in diabetes technology, one major challenge remains: preventing hypoglycemia while maintaining excellent glucose control. That is why researchers are developing glucose-responsive insulin, often called “smart” insulin. Instead of delivering a fixed amount of insulin regardless …

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The First Disease-Modifying Treatment After a Type 1 Diabetes Diagnosis: Why Teplizumab Is Changing the Conversation

Pediatric endocrinologist discussing teplizumab treatment options with a family following a new type 1 diabetes diagnosis.

For decades, treatment after a type 1 diabetes diagnosis focused almost entirely on insulin replacement and blood glucose management. While advances in technology have improved care, clinicians have had few ways to address the autoimmune process driving beta-cell loss. That is beginning to change. With the FDA’s expansion of teplizumab-mzwv …

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Should Patients Still Be Using Flash CGM? Navigating the Shift to Real-Time Monitoring

Patient with a continuous glucose monitor reviewing glucose data on a smartphone while transitioning from flash CGM to real-time CGM technology.

As diabetes technology continues to evolve, clinicians are increasingly faced with an important question: should patients still be using flash continuous glucose monitoring (CGM), or is it time to switch to real-time CGM? While flash CGM systems have significantly improved glucose monitoring and patient engagement over traditional fingerstick testing, real-time …

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Should Hospitalized Patients Keep Their CGMs and Insulin Pumps? The 2026 Standards Say Yes

Hospitalized patient using a continuous glucose monitor and insulin pump while reviewing glucose data on a smartphone under clinical supervision in a modern hospital room.

For years, hospital admission often meant disconnecting patients from their personal diabetes devices. Continuous glucose monitors (CGMs) and insulin pumps were frequently removed, even when patients had used them successfully at home. However, the 2026 American Diabetes Association (ADA) Standards of Care introduce a significant shift in how hospitals approach …

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What Really Happens When Patients Stop Insulin Without Telling Their Doctor?

Patient with diabetes sitting at a table with insulin supplies and glucose monitoring equipment, illustrating the risks of stopping insulin therapy without medical supervision.

For many people living with diabetes, insulin is more than a medication—it is a lifeline. Yet despite its critical role, some patients stop taking insulin without informing their healthcare provider. The reasons vary widely and may include medication costs, treatment fatigue, fear of side effects, weight gain concerns, or misunderstandings …

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The Overnight Danger Many Clinicians Miss: Why Nighttime Hypoglycemia Still Matters

Sleeping patient with diabetes beside a continuous glucose monitor showing low blood sugar levels during the night, illustrating nocturnal hypoglycemia risk.

Many healthcare providers focus heavily on daytime glucose control, yet some of the most dangerous hypoglycemic episodes occur while patients are asleep. Despite major advances in insulin therapy and glucose monitoring, nocturnal hypoglycemia remains a significant clinical concern for people living with diabetes. Because symptoms often go unnoticed during sleep, …

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The Corticosteroid Conundrum: Managing Steroid-Induced Hyperglycemia in Primary Care

Blood glucose monitor beside corticosteroid medication bottle and diabetes log illustrating steroid-induced diabetes management in primary care.

Patients treated with corticosteroids for asthma, COPD exacerbations, rheumatologic disease, inflammatory bowel disease, or cancer-related complications often develop significant elevations in blood glucose. In many cases, these patients have no prior history of diabetes. Yet within days of therapy initiation, blood glucose levels can rise dramatically, creating a challenging clinical …

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Misdiagnosed as Type 2? Why We Need to Screen More Adults for LADA

Doctor explaining LADA diabetes screening to an adult patient previously diagnosed with type 2 diabetes during a clinical consultation.

Up to 10% of adults diagnosed with type 2 diabetes may actually have Latent Autoimmune Diabetes in Adults (LADA), yet many cases remain undetected for years. Because symptoms often develop slowly, LADA is frequently mistaken for traditional type 2 diabetes. However, the wrong diagnosis can delay insulin therapy, worsen glucose …

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