For people with painful diabetic neuropathy (PDN), treatment has traditionally focused on controlling burning, stabbing, and shooting pain. However, emerging research on spinal cord stimulation for diabetic neuropathy raises a more intriguing question: Could neuromodulation also improve sensation? Results from the SENZA-PDN clinical trial suggest that some patients receiving high-frequency …
Read More »Could a Simple Blood Test Predict a Heart Event in Type 2 Diabetes?
Could a routine blood sample someday reveal cardiovascular danger that cholesterol, blood pressure, and HbA1c do not fully capture? New research suggests that epigenetic cardiovascular risk prediction could offer a new way to identify people with type 2 diabetes who face a higher short-term risk of major cardiovascular events. Instead …
Read More »Three Decades of Better Type 1 Diabetes Care: Have Complications Actually Declined?
Three decades of advances in diabetes care have transformed how people with type 1 diabetes manage glucose. Insulin pumps, continuous glucose monitoring (CGM), improved insulin analogs, automated insulin delivery, and earlier screening have all changed daily treatment. However, have these advances actually reduced the long-term complications of type 1 diabetes? …
Read More »The Diabetes Foot Emergency Patients May Never Feel Coming
Charcot foot in diabetes can begin with a warning sign that seems almost contradictory: a foot that is hot, red, and swollen but causes surprisingly little pain. For people with diabetic peripheral neuropathy, reduced sensation may hide the severity of the problem. As a result, patients may continue walking on …
Read More »One Drug Isn’t Enough: When Should Clinicians Combine Treatments for Painful Diabetic Neuropathy?
Finding the right diabetic neuropathy pain treatment can be challenging when a well-chosen first medication provides only partial relief. Burning, shooting pain, tingling, and allodynia can continue to disrupt sleep, mobility, mood, and daily function. Fortunately, clinicians do not always have to choose between abandoning a partially effective drug and …
Read More »Diagnosed Younger: Does Type 1 Onset Shape Later Risk?
Does being diagnosed with type 1 diabetes at age 6 carry the same long-term risks as being diagnosed at 16? Researchers have been asking that question for years. Increasingly, evidence suggests that age at type 1 diabetes onset may help explain differences in complication patterns later in life. However, age …
Read More »Beyond hs-CRP: Could suPAR Reveal Hidden Heart Risk in Type 2 Diabetes?
People with type 2 diabetes can face substantial cardiovascular risk even when clinicians address familiar risk factors such as LDL cholesterol, blood pressure, smoking, and blood glucose. Could another blood marker help reveal some of the risk that remains? Emerging research on the suPAR biomarker in diabetes suggests it may …
Read More »Normal Blood Sugar, But Still in DKA? The Hidden Danger of Euglycemic Ketoacidosis
Euglycemic diabetic ketoacidosis can challenge one of the most familiar clinical shortcuts in diabetes care: DKA should come with markedly elevated glucose. In patients taking sodium-glucose cotransporter 2 (SGLT2) inhibitors, however, dangerous ketoacidosis may develop while glucose remains normal or only modestly elevated. As a result, euglycemic DKA in patients …
Read More »Can AI and Digital Pathology Detect Diabetic Kidney Disease Earlier?
Artificial intelligence is rapidly changing how healthcare professionals diagnose disease. But can computers identify kidney damage before it becomes obvious under a microscope? Researchers believe the answer may be yes. The combination of digital pathology, artificial intelligence, and diabetic kidney disease research is opening new opportunities to identify microscopic kidney …
Read More »Could Tiny RNA Molecules Transform the Future of Diabetes Care?
Diabetes research is moving beyond blood sugar measurements and insulin therapy into an exciting new frontier. One of the most promising areas involves microRNAs, tiny RNA molecules that quietly regulate hundreds of genes throughout the body. Although they are microscopic, their influence on insulin production, inflammation, and blood vessel health …
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