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Protein levels in pregnant women, ground fingernail clippings may lead to alternative tests…. Researchers have successfully tested two new potential methods for diagnosing and monitoring diabetes in its standard and gestational form. These tests could be easier, timelier, and more affordable for patients to identify and treat diabetes. The first …

What do alcohol consumption, smoking, obesity, and diabetes have in common… Previous studies have shown that cardiovascular risk factors are linked to cognitive decline leading to Alzheimer’s disease and dementia. However, we don’t currently have effective treatments for Alzheimer’s disease, so the focus is on prevention. Being able to understand …

Single daily injection for type 2 diabetes is mix of lixisenatide and insulin glargine…. Sanofi’s experimental drug LixiLan is a fixed-ratio single daily injection combination of Lyxumia (lixisenatide) and Lantus (insulin glargine) for patients with type 2 diabetes. It can potentially be the first combination of basal insulin and GLP-1 …

Data establishes effectiveness of semaglutide in treatment of type 2 diabetes…. Novo Nordisk is currently the manufacturer for Victoza (liraglutide), a GLP-1 agonist that needs to be injected once daily. However, semaglutide only needed to be taken once weekly, which is more preferred. The main objective of the SUSTAIN-3 trial …

ReShape® is the first non-surgical weight loss procedure for mild to moderate obesity. The dual balloon device is helping patients to achieve life-changing weight loss without surgery. The dual balloon mounted on a flexible shaft that is inserted endoscopicaly in the stomach and filled with saline. It works by restricting …

In this week’s Homerun Slides, we take a look at the value of glycemic control and explore the question of why type 2 diabetes should be aggressively treated… To download the complete set in PowerPoint format, just use this link: The Present and Future of Insulin Therapy in the Era …

Female, 24 years of age, type 2 diabetes and obesity, wants better glucose management and to lose weight. Most of her meals consist of high carb, fast food take out, she skips breakfast and overeats during the evening hours. She has a sedentary lifestyle. She reports being an “all or …

David Levy, MD, FRCP      Preferred treatment: angiotensin blockade It is universally accepted that angiotensin blockade should be preferentially used in hypertensive diabetic patients. Although the evidence for greater cardiovascular risk reduction compared with other drug groups is not overwhelming, the renoprotective benefits in type 2 diabetes, and reduction in renal end …

David Levy, MD, FRCP      Pharmacological treatment: general features The value of ranking antihypertensive agents The near-universal adoption of treatment algorithms using strong recommendations for first-, second-and third-line treatments, habitual for the past 30 years or more, has been challenged by the European Society of Hypertension (ESH, 2007, 2009). The logic of …

David Levy, MD, FRCP      Thresholds and targets for treatment Type 2 diabetes Thresholds and targets for treatment are shown in Table 11.1. There is general agreement that treatment should start once blood pressure is persistently greater than 140/90 mmHg. Targets for treatment have in some cases run ahead of the evidence; …