Initial combination therapy of metformin, pioglitazone, and exenatide might be more effective in reducing HbA1c compared to sequential add-on in new-onset diabetic patients… The purpose of this study is to initiate a therapy regimen that will reduce HbA1c, increase insulin secretion, and increase insulin sensitivity. This therapy will also avoid …
Read More »Characteristics of Untreated Diabetes Patients
Study participants with untreated diabetes were significantly more likely to be male, older, currently smoking, have lower HDL cholesterol levels, higher BMI, non-HDL cholesterol levels, and systolic blood pressure….
Read More »Long-term Effects of Type 2 Diabetes Screening
Does screening help reduce the risk of cardiovascular disease for type 2 diabetes patients?… Previous studies have shown that diabetes screening can reduce the risk of cardiovascular disease (CVD) and myocardial infarction. In addition, diabetes screening also helps in detecting and changing unhealthy behaviors. However, self-rated health is often overlooked …
Read More »Stem Cell Therapy Promising for Type 2 Diabetes
Human embryonic stem cell therapy was recently shown to reverse type 1 diabetes in mice, and now new mouse studies suggest a role for stem cells in the treatment of type 2 diabetes… Obese, diabetic mice treated with a combination of transplanted stem cell-derived pancreatic progenitor cells and insulin-sensitizing drugs …
Read More »Sitagliptin/Simvastatin Combo Tablet for T2DM and Hypercholesterolemia
Sitagliptin/Simvastatin (Juvisync) might be a good option for diabetic patients who want to improve glycemic control and lower cholesterol levels…
Read More »Years Lost and Medical Care Expenditures Associated with Diabetes
Diabetes can have an impact on life expectancy and health expenditures…
Read More »BMI and Stroke Risk among Type 2 Diabetes Patients
There might be an association between obesity with incidence of stroke among type 2 diabetic patients… Diabetes mellitus and obesity are the most common conditions that increase the risk of stroke in the general population. However, not many studies focused on the association between obesity and cardiovascular disease risk among …
Read More »Results of Study on Diet Sodas Should be Treated with Caution Due to Study Limitations
The recent study “Diet Soda Intake Is Associated with Long-Term Increases in Waist Circumference in a Biethnic Cohort of Older Adults: The San Antonio Longitudinal Study of Aging (SALSA)”1 suffers from several limitations, which likely confound the study’s conclusions. The authors note that the waist circumference (abdominal fat) findings were not …
Read More »PPAR Agonists Raise Heart Failure Risk for Pre-diabetic and T2DM Patients
In the meta-analysis of 14 randomized trials, DPP-4 inhibitors were also found to increase cardiovascular risk slightly while the effect of insulin glargine was neutral…. Data was reviewed from 14 randomized controlled trials of 95,502 patients with or at risk for type 2 diabetes taking new or more intensive glucose-lowering …
Read More »Abdominal Muscle and Type 2 Diabetes in Postmenopausal Women
A greater muscle to total abdominal area ratio was associated with lower odds of diabetes…. Skeletal muscle loss with diabetes onset is common and low muscle mass can be a potential risk factor for diabetes. Studies show that glucose storage and consumption by lean muscle are important factors when looking …
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