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Physician oriented

One Drug Isn’t Enough: When Should Clinicians Combine Treatments for Painful Diabetic Neuropathy?

Clinician discussing diabetic neuropathy pain treatment and combination therapy options with a patient using an anatomical foot model.

Finding the right diabetic neuropathy pain treatment can be challenging when a well-chosen first medication provides only partial relief. Burning, shooting pain, tingling, and allodynia can continue to disrupt sleep, mobility, mood, and daily function. Fortunately, clinicians do not always have to choose between abandoning a partially effective drug and …

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Which Diabetes Drug Will Work Best? New Research Puts Precision Prescribing to the Test

Precision diabetes treatment concept showing sitagliptin, canagliflozin, and pioglitazone with glucose monitoring and personalized care tools.

Precision diabetes treatment aims to answer a question clinicians and patients face every day: which diabetes drug is most likely to work best for this particular person? A new analysis from the TriMaster crossover trial offers an important clue. Researchers compared several precision-medicine strategies for predicting responses to sitagliptin, canagliflozin, …

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Why Does Eating Less Improve Insulin Sensitivity? Ceramides May Hold Part of the Answer

Healthy meal illustrating how calorie restriction may affect ceramides, adiponectin, and insulin sensitivity.

Why does eating less sometimes improve insulin sensitivity beyond what we might expect from weight loss alone? Human research points to an intriguing connection between ceramides, insulin resistance, and adiponectin. Findings from the CALERIE research program suggest that sustained, moderate calorie restriction changes circulating bioactive lipids in ways that may …

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GLP-1s and Vision Loss: What Prescribers Should Know About the Emerging NAION Signal

Patient eye with semaglutide injection illustrating the potential GLP-1 NAION risk and sudden vision loss.

GLP-1 receptor agonists have transformed type 2 diabetes and obesity treatment, but a rare vision safety signal deserves clinicians’ attention. Emerging evidence has raised concerns about a potential NAION risk with GLP-1 therapy, particularly with semaglutide (Ozempic, Rybelsus, and Wegovy). Non-arteritic anterior ischemic optic neuropathy (NAION) can cause sudden, usually …

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The Hidden Hyperglycemia Trigger: When Dehydration Makes Blood Sugar Worse

Person with diabetes reaching for water beside a glucose meter, illustrating how dehydration can worsen high blood sugar.

For people with diabetes, an unexpected glucose spike may have a less obvious cause than food or missed medication. Dehydration and high blood sugar can create a self-reinforcing cycle. When the body loses too much fluid, glucose becomes more concentrated in the bloodstream. At the same time, rising glucose can …

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Your Patient Is Taking a Compounded GLP-1. Now What?

Physician discussing compounded GLP-1 medication safety with a patient during a clinical consultation, with injectable medication vials and a syringe on the desk.

As demand for GLP-1 receptor agonists continues to outpace supply, many patients have turned to compounded medications obtained through telehealth companies, medical spas, wellness clinics, and compounding pharmacies. While these products may improve access for some individuals, they also introduce important clinical, regulatory, and medicolegal challenges. Providers increasingly encounter patients …

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Team-Based Diabetes Management: Building Clinical Partnerships That Actually Work

A multidisciplinary diabetes care team including a doctor, pharmacist, dietitian, and community health worker collaboratively reviewing patient data.

Effective diabetes care doesn’t happen in isolation. With millions of Americans living with diabetes, managing this chronic disease requires more than just a single doctor’s input. Team based diabetes care brings together primary care providers, pharmacists, dietitians, educators, and community health workers to create a more personalized and coordinated approach. …

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Making Diabetes Care Culturally Responsive: Tools for Personalized Counseling and Education

A diverse group of patients engaging in a diabetes education session with a South Asian female doctor explaining glucose monitoring, surrounded by healthy foods and educational tools.

Diabetes doesn’t look the same for every patient—so why should the care plan? Culturally tailored diabetes care recognizes that one-size-fits-all approaches often fall short in reaching patients from different backgrounds. Whether it’s language, food traditions, or health beliefs, culture plays a critical role in diabetes self-management. This article explores how …

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When Diabetes Isn’t the Main Problem: Managing Comorbidities Without Losing Focus

Medical stethoscope, glucose meter, and a clipboard showing icons for heart, kidneys, and brain, symbolizing comorbidities in type 2 diabetes management.

Living with type 2 diabetes often means managing more than just blood glucose. For many patients, conditions like cardiovascular disease, chronic kidney disease, or depression take center stage in their care plan. When diabetes isn’t the main problem, how do you keep glucose control on track without compromising treatment for …

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CGM in Primary Care: Bridging the Endocrinology Gap

A smartphone displaying CGM glucose data surrounded by diabetes monitoring tools including a stethoscope, insulin pen, syringe, and CGM sensor on a clinic desk.

Could continuous glucose monitoring (CGM) soon become the norm in primary care? Once considered a specialty tool reserved for endocrinologists, CGM is now recommended far earlier in diabetes treatment — even for patients with type 2 diabetes on basal insulin alone. Despite these guideline shifts, primary care adoption has lagged. …

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