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Production Assistant, Diabetes In Control

Defining Obesity

Is obesity a disease or a lifestyle choice? Follow the link to share your opinion and see what your colleagues think.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #160: Immunopathogenesis of Type 1 Diabetes in Western Society Part 3

Insulin itself is a prototypical TRA, its synthesis being virtually restricted to pancreatic beta cells. Thymic insulin production is critical for establishing self-tolerance to beta cells; simply abolishing insulin expression in the thymus leads to the rapid onset of autoimmune diabetes even in mice lacking a diabetogenic genetic background [26]. In humans, thymic insulin expression is modulated by allelic variation and epigenetic effects at the insulin gene locus; this effect is largely mediated by a polymorphic variable nucleotide tandem repeat (VNTR) sequence.

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HbA1c Reliability

When is the HbA1c not reliable?

A. Recent blood transfusion
B. Renal failure
C. Medication use (e.g. aspirin)
D. G6PD deficiency
E. All of the above

Follow the link for the answer.

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