Small but frequent activity helps improve insulin concentrations and sensitivity in children with excess weight and obesity.

According to a recent study, which of the following is true among patients with type 2 diabetes (T2DM) and recent acute coronary syndrome (ACS)?

A. The risk for major adverse cardiovascular events (MACE) significantly increased with systolic blood pressure (SBP) less than 130 mm Hg.
B. The risk for MACE significantly increased with diastolic BP (DBP) less than or equal to 80 mm Hg.
C. The risk for MACE significantly decreased with SBP less than 130 mm Hg.
D. The risk for MACE significantly decreased with DBP less than or equal to 80 mm Hg.
E. A&B
F. C&D

Follow the link for the answer.

Would you consider recommending a CGM for your patients who have prediabetes and obesity? Follow the link to share your opinion and see what your colleagues think.

In this week's Homerun Slides, another question from the Adrenal category in Dr. Claude Lardinois' Endocrinology Jeopardy! This week's clue: 44-year-old male with hypertension, headache, tachycardia, and hyperhidrosis.

Genes and environment: a moving target? Studies from multiple populations have shown shifts of the typical HLA class II gene associations during the last few decades. Indeed, fewer patients carry the high risk heterozygous HLA-DR/DQ genotype, except among younger children [59–63], in whom the disease is becoming more common [4]. In contrast, more patients now carry moderate risk HLA types and genotypes. Such shifts in HLA associations may be explained by stronger environmental pressures that enhance HLA-mediated genetic predisposition and/or broaden the spectrum of diabetogenic gene–environment interactions. Viruses, and especially enteroviruses, rank at the top of the list of environmental factors that have been linked to T1DM.

The best and most affordable treatment for type 2 diabetes

Adults with high levels of HbA1c may be at risk of lowered adherence to diabetes medication during poor management of depression.

Older adults with diabetes may be able to benefit from specific exercise recommendations.

Depression and new diagnosis of diabetes in older adults can increase time to disability.

Study compares enhanced patient care experience with standard shared medical appointments to determine if a significant benefit will result.