Amylin Pharmaceuticals and Takeda Pharmaceutical announced that they have suspended clinical activities in an ongoing Phase 2 study examining the safety and effectiveness of the investigational combination therapy pramlintide/metreleptin for the treatment of obesity. The clinical study was voluntarily halted to investigate a new antibody-related laboratory finding with metreleptin treatment …
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What Is the Diabetes Belt?
The Southeastern US has been dubbed the “diabetes belt” with 644 mostly southern counties presenting above average rates of diabetes, according to new research by the CDC. There are more than 18 million diabetes sufferers nationwide, with a state pattern emerging for overall averages that matches known risk factors like …
Read More »Coffee May Lower Stroke Risk for Women
Women who drink more than one cup of coffee a day could reduce their risk of stroke by 22% to 25%. A new study followed 34,670 Swedish women, ages 49 to 83, for an average of 10.4 years. Women who reported drinking little or no coffee had a higher risk …
Read More »Soy Not Effective on Glycemic Control
Previous studies have suggested that soy intake may carry beneficial effects on glycemic control, but human intervention studies have yielded mixed results. A recent meta-analysis of 24 trials and more than 1,500 subjects found that soy consumption does not significantly affect measures of glycemic control. Researchers noted that there was …
Read More »Carb Counting vs. Glycemic Load to Determine Insulin Bolus?
How many carbs you eat might be less important for your blood sugar than your food’s glycemic load….
Read More »Old Mitochondria May be Responsible for Neuropathy in the Extremities
The finding may eventually lead to new ways to fight neuropathy, a condition that often accompanies other diseases including HIV/AIDS, diabetes and circulatory disorders….
Read More »Identifying Patients Who Can Benefit from Preventive Interventions
A1c and cardiovascular risk scores identify those who can benefit from preventive interventions, according to the ADDITION study….
Read More »Physician’s Empathy Associated with Positive Clinical Outcomes in Diabetic Patients
A physician’s empathy is an important factor associated with clinical competence….
Read More »Predicting the Best Response from Metformin via Genetic Markers
Common variants are associated with glycemic response to metformin in Type 2 diabetes….
Read More »Otelixizumab Developed by GSK and Tolerx Fails in Type 1 Diabetes Study
Tolerx, Inc., and GlaxoSmithKline (GSK) announced that the Phase 3 DEFEND-1 study of otelixizumab, an investigational humanized anti-CD3 monoclonal antibody, did not meet the primary efficacy endpoint of change in C-peptide at month 12 in patients with new-onset autoimmune Type 1 diabetes….
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