The FDA approved a new angiotensin-receptor blocker (ARB), azilsartan medoxomil (Takeda Pharmaceutical), for the treatment of hypertension in adults. The drug will be available in 80-mg and 40-mg doses, although 80 mg is the recommended dose. The 40-mg dose is available for clinicians who wish to combine the drug …

  The FDA has accepted Bristol-Myers Squibb’s New Drug Application for its first in class drug dapagliflozin, an investigational selective sodium-glucose cotransporter-2 inhibitor (SGLT2), first in class compound for the treatment of adults with Type 2 diabetes.

The study population included 3,554 men and women, age 18 to 30 at baseline, whose weights were followed during six follow-up visits over 20 years. Participants reported their activity levels over the previous year at each visit: high, moderate or low levels (or inconsistent activity if categories changed over time). …

In a meta-analysis of longitudinal cohort studies (ARIC, CARDIA, CHS, FOS, and MESA; 2764 subjects total), the relative risk of mortality was demonstrated to be nearly two times higher for Type 2 diabetes patients with normal weight than for those who were overweight or obese. More specifically, those with normal …

Data from 10 trials were used. The interventions were found to reduce progression to diabetes, while they were found to have no significant effect on all-cause mortality, cardiovascular mortality, and myocardial infarction, and a marginally statistically significant reduction in risk for stroke. In conclusion, Dr. Ingrid K. Hopper noted that …

Which test is the most accurate?…

Excess mortality seen with ultra-tight glucose control in high-risk patients with established Type 2 diabetes persisted despite termination of that arm of the study, researchers warned in mid-term reporting from the ACCORD study….

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with Type 2 diabetes as whites….

Diabetes not only doubles vascular death risk but also substantially raises risk of death from nonvascular causes, including cancer and infectious disease, researchers found….

“Those who had endurance exercise training three times a week looked as young as healthy mice while their sedentary siblings were balding, graying, physically inactive, socially isolated, and less fertile….”