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Diabetes In Control

Practical Diabetes Care, 3rd Ed., Excerpt #6: Type 2 Diabetes: General Introduction

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David Levy, MD, FRCP Introduction: Type 2 Diabetes as a Progressive Condition Glycemia in type 2 diabetes progressively deteriorates with time, usually thought to be related to progressive beta-cell failure. This was demonstrated dramatically in the United Kingdom Prospective Diabetes Study (UKPDS 1998), but the glycemic trends have been less marked …

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Reduced GLP-1 Precedes Type 2 Diabetes

This might be a reason not to use a DPP-4 for those with long standing diabetes… Reduction in the glucose-regulating hormone glucagon-like peptide-1 (GLP-1) appears to occur before the development of type 2 diabetes and obesity, according to new published research. Investigator Kristine Færch, PhD, senior research fellow at the …

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New Diagnosing Criteria Possible for Type 1?

By closely examining currently used diagnostic criteria, researchers evaluated whether it might be possible to diagnose type 1 earlier…. Today, diagnostic criteria for type 1 diabetes includes a glucose value ≥ 126 mg/dL and 2-h glucose values ≥ 200 mg/dL. These glucose values were selected because they correspond with observed …

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DPP-4 Inhibitors Protect against Hypoglycemia

Mice treated with DPP-4 inhibitors also showed an increase in production of their own glucagon… Siri Malmgren, a researcher at Lund University, stated that, “If these inhibitors also prove effective in humans against low blood sugar, then this supports the idea that the area of application of these drugs could …

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Diabetes Screening at the Dentist

Dental visits may allow for diabetes screening and monitoring glucose control in at-risk patients… A new study suggests that using gingival crevicular blood, collected during dental visits, for HbA1c testing produced values that were nearly identical to those obtained using finger stick blood. Correlation was 0.991 between the HbA1c values …

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Predicting Type 1 Diabetes

It may be possible to predict the development of type 1 diabetes in young children by measuring the presence of autoantibodies in the blood… This comes from new data from The Environmental Determinants of Diabetes in the Young (TEDDY) study. Lead researcher Åke Lernmark, MD, PhD, of Lund University, said …

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