David Levy, MD, FRCP Introduction Infections in patients with diabetes are a persistent trap for both the inexperienced and world-wise physician. Whenever someone with diabetes presents unwell, always consider the possibility of infection. High blood glucose levels predispose to some acute infections, especially postoperatively, but other mechanisms are involved, for example …

"Heloderma suspectum" is the buzz phrase this week. It turns out that he is a cousin of Martin, the green lizard of Geico fame, and was the first reptile to make using incretins in diabetes therapy possible. This class has changed the ideas we previously had about diabetes management and …

David Levy, MD, FRCP Drugs acting on the incretin system (entero-insular axis) (Fig. 6.2) The incretin effect Bayliss and Starling inferred the existence of gut-derived substances affecting carbohydrate metabolism more than a century ago, but the incretin effect was not described until 1969: the observation that for a given achieved level …

Peter Katzmarzyk, PhD, discusses the growing problem of childhood obesity which frequently contributes to the earlier development of adult type 2 diabetes. He also mentions that, particularly in the southern U.S., there are more and more incidences of type 2 in children and teens being reported. More videos with Dr. …

Peter Katzmarzyk, PhD, talks about how, even though dieting and exercise should be part of every patient’s regimen, this can be extremely difficult in certain places. He says there are many ways we could improve the physical environment, however, in our towns and cities, including simple things like adding sidewalks …

American College of Cardiology Foundation Free/iOS & Android   The ASCVD Risk Estimator is published jointly by the American College of Cardiology (ACC) and the American Heart Association (AHA) to help health care providers and patients estimate 10-year and lifetime risks for atherosclerotic cardiovascular disease (ASCVD) using the Pooled Cohort …

Diabetic peripheral neuropathy can have an effect on balance… Previous studies show that patients with diabetic peripheral neuropathy (DPN) have an altered gait strategy and a fivefold increased risk of falling. Falling is a major health risk, especially with disease progression and in the elderly. Diabetic patients with peripheral neuropathy …

Older individuals are at an increased risk for cardiac autonomic nervous dysfunction…

A multinational team of researchers studied data from over 16,000 patients in the SAVOR-TIMI 53 trial…. Saxagliptin (Onglyza) is a commonly prescribed dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. An international team of researchers examined the effects of saxagliptin on glycemic stability and β-cell function in the …

But the association with between hypertension, diabetes, and dementia is not clear…. Previous studies have found a correlation between individuals with hypertension and diabetes, and the subsequent development of dementia. The purpose of this cross-sectional study was to analyze the effect of diabetes and hypertension on cognitive scores conducted on …