Retrospective cases showed that some patients treated with canagliflozin had severe diabetes ketoacidosis… The Food Drug Administration (FDA) had previously reported that Invokana® (canagliflozin) had cases of diabetes ketoacidosis (DKA) in type 2 diabetes; however, a recent study done by Janssen Research & Development shows that patients who were taking …
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Diabetes and Hypertension Linked to Grip Strength
Researchers found that the strength of your grip could provide clues to undetected diabetes or high blood pressure, especially if you’re “skinny fat.” That means you’re within the normal range on the body mass index (BMI), but your fat-to-lean muscle ratio leans more toward the fat part, about 25 percent …
Read More »Exercising Early in Life Reduces Diabetes Risk Later
The findings, based on 300 children whose insulin resistance was monitored annually from ages 9 to 16, may indicate that reducing the peak in insulin resistance in adolescence lessens the strain on insulin-producing cells and reduces the risk of diabetes later in life, researchers said. Insulin resistance rises dramatically from …
Read More »Metformin Helps to Lower LDL Cholesterol
A new study finds that in more than 1,000 patients that the administration of metformin in patients suffering from type 2 diabetes led to a change in metabolite levels. According to the authors, this was associated with a significantly decreased level of LDL cholesterol, which is under strong suspicion to …
Read More »Quell Wearable Device – An Impressive Advance for Treating Chronic Pain
Quell chronic pain management device is an over-the-counter product (no prescription needed). It uses nerve stimulation to treat multiple types of chronic pain, including diabetic neuropathy and fibromyalgia. Quell stands out as one of the only FDA-cleared non-drug therapies for chronic pain relief, eliminating many of the side effects that …
Read More »Case Study: The Pathology of Nesidioblastosis
An African-American male was diagnosed with heart failure at age 38 due to severe hypertension. At age 40, patient weighed 166lbs and he had normal glucose tolerance test. Three years later, patient weighed 275 lbs due to unknown reason and he was diagnosed with type I diabetes based on a …
Read More »Editor’s Note, DCMS #254
Have you ever heard of nesidioblatosis? More importantly, have you ever put that condition together with diabetes? In our new Near Miss Case Study section, we take a look at how these conditions could totally mask what is really going on with a patient. Our Homerun Slides move to the …
Read More »Editor’s Note, GLP-1 Analog Special Edition, August 2015
The use of GLP-1 analogs have become commonplace in the prescribers’ regimen and many practitioners try different combinations to maximize the potential of this class of drugs. Using a GLP-1 analog with basal insulin has become the norm and this month we have the results of a combination product that …
Read More »The Present and Future of Insulin Therapy Part 5
In this week’s Homerun Slides, we take a look at the prevention of beta cell failure in type 2 diabetes…
Read More »The Present and Future of Insulin Therapy Part 4
In this week’s Homerun Slides, we take a look at the beta cell mass and pathogenesis of type 2 diabetes… To download the complete set in PowerPoint format, just use this link: The Present and Future of Insulin Therapy in the Era of Pathophysiologic Treatment of T2DM, Part 4 …
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