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Diabetes In Control

Chlorthalidone More Effective Than Hydrochlorothiazide in Lowering Blood Pressure

Although low-dose thiazide-type diuretics are recommended as initial therapy for most hypertensive patients, chlorthalidone has significantly reduced stroke and cardiovascular end points in several landmark trials. But hydrochlorothiazide remains favored in practice. Most clinicians assume that the drugs are interchangeable, but their antihypertensive effects at lower doses have not been …

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