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Clinical Presentations

PowerPoint Presentations that you can use for your own presentations. All presentations are created by Medical professionals in diabetes care.

Tackling Therapeutic Inertia: Why Providers Delay in Diabetes Care

A female doctor discusses HbA1c results with a male patient in a clinical office; the computer screen displays a chart with the message "HbA1c > 8% – ACTION NEEDED," while medical devices and a "Follow-up Needed" folder sit on the desk.

In diabetes care, “therapeutic inertia” refers to the failure to escalate or modify treatment when a patient’s glucose control is suboptimal. Even now — when newer, more effective treatments and monitoring tools are widely available — therapeutic inertia in diabetes remains a stubborn barrier. Providers often wait too long before …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #162: Immunopathogenesis of Type 1 Diabetes in Western Society Part 5

Autoimmunity persists in many patients even many years after diagnosis: Studies in patients with long disease duration suggest that beta-cell function may persist long after diagnosis in a significant proportion of patients. There is also evidence suggesting the co-existence of some low level of regeneration with chronic autoimmunity, as islet autoimmunity may also persist or perhaps be reactivated years after diagnosis. Indeed, significant proportions (30–40%) of islet or pancreas transplant recipients express one or more autoantibodies when evaluated prior to transplantation. Moreover, persisting autoreactive T-cell responses detected prior to transplantation correlate with islet graft failure on follow-up.

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