Type 2 Diabetes

For many people with diabetes, lowering LDL cholesterol is just as important as controlling blood sugar. However, not everyone reaches their cholesterol goals with statins alone, and injectable PCSK9 inhibitors can be inconvenient or intimidating. Now, a new option has arrived. The FDA has approved the first oral PCSK9 inhibitor, …

For many people living with type 2 diabetes, the biggest challenge is not finding an effective medication. It is being able to afford it. That reality may begin to change now that the U.S. Food and Drug Administration (FDA) has approved the first generic versions of Farxiga (dapagliflozin), potentially making …

Night-shift work keeps hospitals, factories, transportation systems, and emergency services running around the clock. However, while society benefits from overnight workers, their metabolic health often pays the price. Recent continuous glucose monitoring (CGM) studies have shown that shift work is strongly associated with greater glycemic variability in people with diabetes, …

Finding the right diabetes medication often involves trial and error. One patient may respond well to a GLP-1 receptor agonist, while another sees little benefit from the same treatment. As a result, clinicians frequently adjust medications before finding the most effective option. What if doctors could test a patient’s response …

Type 2 diabetes has traditionally been viewed as a disease driven by insulin resistance and declining pancreatic beta-cell function. However, researchers are now looking much deeper into the cell itself. Increasing evidence suggests that mitochondrial dysfunction in diabetes may be a key factor linking impaired energy production, chronic inflammation, oxidative …

For years, diabetes care has emphasized one simple message: exercise regularly. While that advice remains essential, researchers are now asking a more specific question. Could when you exercise be just as important as how much you exercise? Emerging evidence suggests the answer may be yes. The growing field of chronotherapy, …

When most people think about diabetes, they picture the pancreas, insulin, or blood sugar. However, researchers are increasingly asking a different question: what if another organ has been quietly influencing glucose metabolism all along? Surprisingly, the answer may be the skeleton. For decades, bone was viewed primarily as the body’s …

Diabetes often develops silently for years before blood sugar levels become high enough for a diagnosis. What if tiny biological packages circulating in the bloodstream could reveal those hidden changes long before symptoms appear? Researchers are increasingly studying how exosomes may serve as biomarkers for diabetes because these microscopic messengers …

Managing diabetes has never offered more therapeutic options. Continuous glucose monitors (CGMs), automated insulin delivery systems, GLP-1 receptor agonists, SGLT2 inhibitors, and individualized treatment plans have transformed patient care. Yet despite these advances, many people with diabetes continue to struggle, not because treatments are ineffective, but because the overall workload …

Diabetes is often diagnosed only after blood sugar levels have already risen above normal. However, what if the earliest warning signs appeared years before glucose levels changed? That question is driving exciting research into metabolomics, a rapidly growing field that analyzes tiny molecules produced during normal metabolism. Instead of focusing …