Type 1 Diabetes

Could preventing a common viral infection also prevent some cases of type 1 diabetes? Researchers have pursued that question for decades, and the first human vaccine studies are providing important clues. The idea of using a Coxsackievirus vaccine to help prevent type 1 diabetes focuses on certain Coxsackie B viruses, …

Donor islet transplantation has long offered an intriguing possibility for people with severe type 1 diabetes: restore the body’s ability to make insulin instead of only replacing insulin from the outside. However, there has always been a major tradeoff. Patients need powerful immunosuppressive drugs to keep transplanted cells alive, and …

Artificial intelligence is entering diabetes care in a surprisingly quiet way. Rather than appearing as a chatbot or separate decision-support tool, increasingly sophisticated algorithms are being built into automated insulin delivery systems. Adaptive insulin pump hardware can work with continuous glucose monitor (CGM) data, recent insulin delivery, and changing glucose …

Diabetes research is moving beyond blood sugar measurements and insulin therapy into an exciting new frontier. One of the most promising areas involves microRNAs, tiny RNA molecules that quietly regulate hundreds of genes throughout the body. Although they are microscopic, their influence on insulin production, inflammation, and blood vessel health …

For more than 100 years, the Bacillus Calmette-Guérin (BCG) vaccine has been used worldwide to help prevent tuberculosis. However, researchers are now exploring another possible role for this familiar vaccine. Recent studies suggest that the BCG vaccine may play a role in treating type 1 diabetes by modifying the immune …

Many people with type 1 diabetes live with the constant fear of blood glucose dropping too low. Even today’s most advanced automated insulin delivery systems cannot actively raise glucose once levels begin to fall. Instead, they can only reduce or suspend insulin delivery. A dual-hormone artificial pancreas system changes that …

The transition from pediatric to adult diabetes care is one of the most challenging periods in the lives of young people with diabetes. While many adolescents successfully manage their condition with the support of pediatric diabetes teams, moving into adult healthcare often coincides with worsening blood glucose control, missed appointments, …

Receiving a diagnosis of type 1 diabetes can feel overwhelming. Yet for many adults, the weeks or months that follow bring an unexpected twist. Blood glucose levels often become easier to control, insulin needs decrease, and some people wonder if their diabetes is actually improving. This temporary period is known …

For more than a century, insulin therapy has remained the cornerstone of treatment for type 1 diabetes. While continuous glucose monitors, insulin pumps, and automated insulin delivery systems have dramatically improved diabetes management, they still do not replace the body’s natural ability to regulate blood sugar. As a result, researchers …

Finding the right diabetes medication often involves trial and error. One patient may respond well to a GLP-1 receptor agonist, while another sees little benefit from the same treatment. As a result, clinicians frequently adjust medications before finding the most effective option. What if doctors could test a patient’s response …