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Tag Archives: Obesity treatment

Amylin Is Making a Comeback: Why This Forgotten Hormone Is Back in the Spotlight

Medical illustration showing amylin hormone activity alongside insulin therapy, highlighting next-generation amylin-based treatments for diabetes and obesity.

For years, glucagon-like peptide-1 (GLP-1) receptor agonists have dominated conversations about diabetes and obesity treatment. However, another hormone is quietly returning to the spotlight. Amylin diabetes therapy is making a comeback as researchers develop a new generation of drugs designed to improve blood glucose control and support weight management. Amylin …

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The Glucagon Paradox: Why Activating a “Blood Sugar Hormone” Can Improve Metabolic Health

Medical illustration showing GLP-1, GIP, and glucagon receptors working together to improve metabolism, weight loss, liver health, and blood glucose control in triple agonist diabetes therapy.

For decades, glucagon has been viewed as insulin’s opposite. While insulin lowers blood glucose, glucagon raises it by signaling the liver to release stored sugar into the bloodstream. Because of this, glucagon has traditionally been considered a hormone to suppress in people living with type 2 diabetes. However, modern research …

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Your Patient Is Taking a Compounded GLP-1. Now What?

Physician discussing compounded GLP-1 medication safety with a patient during a clinical consultation, with injectable medication vials and a syringe on the desk.

As demand for GLP-1 receptor agonists continues to outpace supply, many patients have turned to compounded medications obtained through telehealth companies, medical spas, wellness clinics, and compounding pharmacies. While these products may improve access for some individuals, they also introduce important clinical, regulatory, and medicolegal challenges. Providers increasingly encounter patients …

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Maxed Out on Medications, Not Ready for Surgery: Is Metabolic Endoscopy the Missing Middle Ground?

Physician performing a metabolic endoscopy procedure showing endoscopic treatment of the stomach and digestive tract for type 2 diabetes management.

For many people living with type 2 diabetes, treatment eventually reaches a frustrating crossroads. Despite multiple medications, including GLP-1 receptor agonists, SGLT2 inhibitors, and insulin, glycemic targets may remain difficult to achieve. Meanwhile, bariatric surgery can produce major metabolic benefits, but its invasiveness limits acceptance for many patients. This treatment …

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Protecting Muscle While Treating Obesity: New Protein Targets for Older Adults on GLP-1s

Older adult performing strength training with protein-rich foods and muscle anatomy model, illustrating sarcopenia prevention during GLP-1 therapy and obesity treatment.

The rise of highly effective GLP-1 receptor agonists and dual incretin therapies has transformed obesity treatment. Medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) are helping patients achieve levels of weight loss that were previously difficult to attain without bariatric surgery. However, as clinicians celebrate these advances, a …

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When GLP-1 Therapy Plateaus: What Clinicians Should Do Next

Clinician reviewing patient progress during a GLP-1 plateau with metabolic trend chart on computer screen

Everything seems to be working perfectly until it suddenly isn’t. A patient is losing weight steadily, HbA1c levels are improving, and confidence is high during every follow-up visit. Then progress slows. The scale barely changes. Blood sugar readings stop improving. Patients start asking whether the medication has stopped working, while …

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GLP-1 Therapy and Muscle Loss: Are We Overlooking Sarcopenia Risk?

Medical illustration showing GLP-1 therapy, muscle mass preservation, weight loss, dumbbells, and body composition changes.

Losing 30 pounds may sound like an undeniable success story. However, what if part of that weight loss comes from muscle instead of fat? As more patients use GLP-1 medications such as semaglutide and tirzepatide, clinicians are starting to ask an important question: are these drugs quietly contributing to the …

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Fragmented Care in the GLP-1 Era: What Happens When Multiple Providers Prescribe the Same Therapy?

Patient navigating GLP-1 therapy while multiple healthcare providers coordinate diabetes and obesity treatment across telehealth and clinical settings.

A patient starts semaglutide through a telehealth platform, receives nutrition advice from a wellness clinic, and later visits a primary care physician for worsening gastrointestinal symptoms. None of the providers can see the full treatment picture. Situations like this are becoming increasingly common as GLP-1 medications move across multiple corners …

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Are GLP-1 Drugs Being Prescribed Too Early? Rethinking Risk Thresholds in Diabetes Care

Balance scale comparing healthy lifestyle habits and GLP-1 diabetes medications in a modern medical office setting

A patient loses 30 pounds, lowers their A1C, and improves their blood pressure within months of starting a GLP-1 medication. Stories like these are hard to ignore, and they have helped fuel growing enthusiasm around drugs like Ozempic, Wegovy, and Mounjaro. Yet as prescriptions continue to expand beyond high-risk diabetes …

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Will Generic GLP-1 Drugs Change Diabetes Care? What Clinicians Should Expect Next

Generic GLP-1 drug injection pens and medication boxes representing the future of affordable diabetes care in a clinical setting.

The rapid rise of GLP-1 receptor agonists has transformed diabetes treatment and obesity management over the past decade. However, high prices and limited insurance coverage continue to restrict access for many patients. As patents evolve and global pharmaceutical markets shift, conversations about lower-cost GLP-1 therapies are gaining momentum. Clinicians are …

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